摘要
目的 调查分析上海市嘉定区新成路街道老年人主观认知下降(subjective cognitive decline,SCD)发生的相关影响因素,为进一步预防SCD提供依据.方法 调查于2022年1月-2022年12月在上海市嘉定区新成路街道社区卫生服务中心参加免费体检的≥60岁老年人共961例.采用单因素回归筛选具有临床意义的常见观察指标;采用多元回归模型探讨SCD发生的影响因素.结果 共有902例居民参与了本项研究(男性373例、女性529例),入组老年人群SCD检出率为21.1％.单因素Logistic回归分析结果显示:性别、年龄、学历、受教育年限、尿酸、血红蛋白、糖尿病、冠心病、身体水分含量、去脂体重、基础代谢、无机盐、肌肉量、蛋白质量及衰弱分期等参数与SCD具有显著相关性(P＜0.05).多因素Logistic回归分析结果显示:受教育年限为SCD的独立保护因素[OR=0.90,95％CI:0.85～0.95,P＜0.001];女性[OR=1.68,95％CI:1.08～2.62,P=0.021]、衰弱[OR=2.51,95％CI:1.84～3.40,P＜0.001]为SCD的独立危险因素.结论 上海市嘉定区新成路街道老年人群SCD检出率为21.1％.女性和衰弱是SCD的危险因素,受教育年限是其保护因素.
Abstract
Objective To investigate the prevalence and influencing factors of subjective cognitive decline(SCD)among community-dwelling elderly.Methods A total of 961 residents aged ≥60 years undergoing health check-up in Xincheng Community Health Service Center of Shanghai Jiading District from January 2022 to December 2022 were enrolled in the study.The cognition status was avaluated with subjective cognitive decline questionnaire 9(SCD-Q9).The influencing factors of SCD were examined with univariate and multivariate Logistic regression analysis.Results Among 961 subjects,902 completed the survey,including 373 males and 529 females,SCD was detected in 190 cases with a prevalence rate of 21.1% .Univariate Logistic regression analysis showed that sex,age,education background,years of education,uric acid,hemoglobin,diabetes,coronary heart disease,body water content,fat-free body weight,basal metabolism,inorganic salt contents,muscle mass,protein mass,and frailty were significantly correlated with SCD(P＜0.05).Multivariate Logistic regression analysis showed that years of education(OR=0.894,95% CI:0.850-0.939,P＜0.001)was an independent protective factor for SCD,female sex(OR=1.455,95% CI:1.015-2.086,P=0.041)and frailty(OR=2.639,95% CI:1.964-3.546,P＜0.001)were independent risk factors for SCD.Conclusion The prevalence rate of SCD was 21.1% among the community-dwelling elderly of the study site;female sex and frailty are risk factors for SCD,while years of education is a protective factor.
基金项目
国家自然科学基金(82271586)
国家自然科学基金(82200970)
国家重点研发计划(2023YFC3604501)
上海市卫生健康委员会科研基金(20234Y0156)
同济大学附属同济医院临床研究培育项目(ITJZD2002-1)
同济大学附属同济医院临床研究培育项目(ITJQN2213)
国家科技期刊平台
NSTL
万方数据