Objective To explore the relationship between myocardial bridging and carotid artery plaque.Methods The study subjects were recruited from hospitalized patients in Nanjing Hospital of Chinese Medicine between January 2022 and July 2024.The carotid artery plaque was analyzed and measured by Philips EPIQ 7 ultrasound instrument.The myocardial bridging was confirmed by coronary CT angiography(CCTA)using Siemens dual-source Force CT.Results A total of 261 participants with a mean age of(64.0±10.4)years were enrolled,and CCTA detected myocardial bridge in 84 cases(32.2%,MB group).Compared to non-MB group,MB group had lower rates of coronary artery disease(25%vs 39%;P=0.03)and left carotid artery plaque(40.5%vs 58.2%;P=0.007).There were no significant differences in the length and thickness of the plaque,and proportion of right carotid artery plaque between two groups(P≥0.14).Univariate and multivariate logistic regression analyses showed that myocardial bridge was significantly associated with lower risks of left carotid artery plaque(OR=0.49 and 0.40,respectively;P≤0.014).Stratified analysis based on age,gender,and coronary heart disease showed no interactions were detected(Pint≥0.19).Conclusion In hospitalized patients,myocardial bridging is independently associated with a reduced risk of left carotid artery plaque.