冠状动脉心肌桥与颈动脉斑块的相关性研究
Association between myocardial bridging and carotid artery plaque
张玉林 1何晨冬 1邹楠 1宋虎 2贾晓峰1
作者信息
- 1. 南京中医药大学附属南京中医院(南京市中医院)医学影像科,南京 210022
- 2. 南京中医药大学附属南京中医院(南京市中医院)超声医学科,南京 210022
- 折叠
摘要
目的 探讨冠状动脉心肌桥(myocardial bridge,MB)与颈动脉斑块的关系.方法 筛选2022年1月-2024年7月因胸痛怀疑冠心病在南京市中医院心内科就诊并行CCTA的368例患者.飞利浦EPIQ 7超声仪测量分析颈动脉斑块;西门子双源ForceCT进行冠脉造影检测心肌桥.结果 研究共计纳入261例参与者,平均年龄(64.0±10.4)岁,心肌桥84例(32.2％).与无心肌桥组患者相比,心肌桥组的冠心病比例较低(25％vs 39％;P=0.03)、左侧颈动脉斑块的比例也较低(40.5％vs 58.2％;P=0.007);颈动脉斑块的长度、厚度以及右侧颈动脉斑块的比例组间无明显差异(P≥0.14).单变量和多变量逻辑回归分析显示,心肌桥组患者发生左侧颈动脉斑块的风险较低(OR分别为0.49和0.40;P≤0.014).基于年龄、性别和冠心病等的分层分析显示MB与这些影响因素间对左侧CAS没有交互作用(Pint≥0.19).结论 在住院患者中,心肌桥与左侧颈动脉斑块发生风险降低独立相关.
Abstract
Objective To explore the relationship between myocardial bridging and carotid artery plaque.Methods The study subjects were recruited from hospitalized patients in Nanjing Hospital of Chinese Medicine between January 2022 and July 2024.The carotid artery plaque was analyzed and measured by Philips EPIQ 7 ultrasound instrument.The myocardial bridging was confirmed by coronary CT angiography(CCTA)using Siemens dual-source Force CT.Results A total of 261 participants with a mean age of(64.0±10.4)years were enrolled,and CCTA detected myocardial bridge in 84 cases(32.2％,MB group).Compared to non-MB group,MB group had lower rates of coronary artery disease(25％vs 39％;P=0.03)and left carotid artery plaque(40.5％vs 58.2％;P=0.007).There were no significant differences in the length and thickness of the plaque,and proportion of right carotid artery plaque between two groups(P≥0.14).Univariate and multivariate logistic regression analyses showed that myocardial bridge was significantly associated with lower risks of left carotid artery plaque(OR=0.49 and 0.40,respectively;P≤0.014).Stratified analysis based on age,gender,and coronary heart disease showed no interactions were detected(Pint≥0.19).Conclusion In hospitalized patients,myocardial bridging is independently associated with a reduced risk of left carotid artery plaque.
关键词
心肌桥/冠状动脉计算机断层扫描血管造影/颈动脉斑块Key words
myocardial bridging/coronary computed tomography angiography/carotid artery plaque引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据