首页|2009-2022年上海市安亭社区恶性肿瘤死亡趋势分析

2009-2022年上海市安亭社区恶性肿瘤死亡趋势分析

Trends of cancer mortality in Anting community of Shanghai,2009-2022

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目的 分析上海市安亭社区2009-2022年恶性肿瘤趋势情况.方法 收集2009-2022年上海市安亭社区人口构成及恶性肿瘤死亡病例数据,统计学分析采用了多个指标,包括粗死亡率、标化死亡率、年度变化百分比(annual percent change,APC)、平均年度变化百分比(average annual percent change,AAPC)、95%置信区间(confidence interval,CI)以及构成比.标化死亡率基于2000年国家统计局普查数据计算.采用Joinpoint回归分析揭示死亡率的年平均变化趋势,对粗死亡率和标化死亡率进行对数转换,并应用网格搜索法、蒙特卡罗置换检验和修正贝叶斯方法确定最佳年度变化趋势曲线.结果 2009-2022年,上海安亭社区总死亡6516例,其中恶性肿瘤2 150例(占33.00%),年平均恶性肿瘤粗死亡率为240.42/10万,男性(307.59/10万)高于女性(172.29/10万),总体癌症粗死亡率变化不显著,但标化死亡率显著下降(AAPC=-2.5%,P<0.001).就粗率来说,肺癌的死亡率增加了 142.1%,并呈现显著性的上升趋势(AAPC=8.6%,P=0.034),而胃癌的标化死亡率下降了 50.3%,并呈现显著性的下降趋势(AAPC=-6.0%,P=0.008).随着年龄的增长,恶性肿瘤死亡率在不断上升,尤其是65岁以上的老年人群,85岁以上达到高峰.男性死因顺位前5位分别是肺癌、胃癌、肝癌、结直肠癌、胰腺癌;女性死因顺位前5位分别为胃癌、肺癌、胰腺癌、结直肠癌、肝癌.结论 上海安亭社区癌症死亡呈上升趋势,尤其在65岁以上.总体标化死亡率下降,但肺癌、结直肠癌等显示上升趋势.性别和年龄对癌症死因有显著影响,提供癌症防控信息,应及时制定措施,加强对恶性肿瘤的早期预防和控制.
Objective To analyze trends of cancer mortality in Anting community of Shanghai from 2009 to 2022.Methods Data of population and cancer death cases in Anting community of Shanghai from 2009 to 2022 were collected,the crude mortality rate,age-standardized mortality rate(ASMR),annual percentage change(APC),average annual percentage change(AAPC)were calculated.ASMR was calculated by Chinese standard population based on the NSO census 2000.Joinpoint regression analysis was used to analyze the average annual trend;the best annual trend curve of mortality rate was determined by the grid search method,Monte Carlo replacement test and modified Bayesian method.Results There were total of 6 516 deaths in Anting community during 2009-2022,of which 2 150(33.00%)were due to malignant tumors.The average annual crude cancer mortality rate was 240.42/105,and the mortality rate in males(307.59/105)was higher than that in females(172.29/105).There were no significant changes in crude cancer mortality rate,while the ASMR showed a significant decline(AAPC=-2.5%,P<0.001).The crude mortality rate of lung cancer increased by 142.1%showing a significant upward trend(AAPC=8.6%,P=0.034);while the ASMR of gastric cancer dropped by 50.3%showing a significant downward trend(AAPC=-6.0%,P=0.008).The cancer mortality increased with age,starting from age of 65 years and peaking at age of 85 years and above.The top 5 leading causes of cancer death for males were lung,stomach,liver,pancreatic and colorectal cancers;for females were stomach,lung,pancreatic,colorectal and breast cancers.Conclusion Cancer deaths in the Anting community of Shanghai are on the rise,especially in the age group of 65+years.The overall standardized mortality rate is decreasing,but lung cancer and colorectal cancer show an increasing trend.The causes of cancer death are associated with gender and age,indicating that measures of cancer prevention and control should be developed accordingly.

malignant tumormortality rateAnting communitytrend analysis

许学海、张丽娟、卢箴劬、沈初、张烨

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同济大学医学院附属安亭镇社区卫生服务中心预防科,上海 201805

同济大学医学院公共卫生与全科医学院,上海 200331

恶性肿瘤 死亡率 安亭社区 趋势分析

2024

同济大学学报(医学版)
同济大学

同济大学学报(医学版)

CSTPCD
影响因子:0.51
ISSN:1008-0392
年,卷(期):2024.45(6)