Objective:To observe the effect of Huangxiong Kangshuan Formula on serum levels of vascular endothe-lial growth factor(VEGF)and neuron specific enolase(NSE)in patients with acute cerebral infarction.Methods:From October 2021 to October 2022,60 patients with acute cerebral infarction who were hospitalized in the Department of En-cephalopathy of Geriatric Center,the First Affiliated Hospital of Anhui University of Chinese Medicine were selected as the research objects.They were randomly divided into the control group and the observation group,with 30 cases in each group.The patients in the control group were given routine treatment according to the treatment plan for acute cerebral in-farction,and the patients in the observation group were treated with Huangxiong Kangshuan Formula on the treatment basis of the control group.The treatment period were both 4 weeks.The changes of serum VEGF and NSE levels,National Insti-tutes of Health Stroke Scale(NIHSS)score,functional independence measure(FIM)score and traditional Chinese medi-cine(TCM)syndrome score were compared between the two groups before and after treatment.Results:After treatment,the serum VEGF levels of the two groups were increased,and the serum NSE levels were decreased,which were better than those before treatment,with the statistical significance(P<0.05).After treatment,the NIHSS scores of the two groups were lower than those before treatment,and the FIM scores were higher than those before treatment,with the statistical sig-nificance(P<0.05).After treatment,the TCM syndrome scores of the two groups decreased,and the scores of the observa-tion group decreased more significantly,with the statistical significance(P<0.05).After treatment,the total effective rate of the observation group(96.67% )was significantly higher than that of the control group(86.67% ),and the difference was statistically significant(P<0.05).Conclusion:The effect of Huangxiong Kangshuan Formula in the treatment of acute ce-rebral infarction is outstanding,which can significantly increase the serum VEGF level,reduce the serum NSE level,and help the recovery of nerve cell function.At the same time,it can also improve the tissue reperfusion caused by insufficient cerebral blood flow and improve the self-care ability of patients.
acute cerebral infarctionHuangxiong Kangshuan FormulaVEGFNSEability to live independently
NETL
NSTL
万方数据
