Distribution characteristics of clinical symptoms and TCM syndrome elements in 734 patients with high risk of chronic obstructive pulmonary disease
Objective:To analyze the characteristics of chronic obstructive pulmonary disease(COPD)in high-risk population and the distribution characteristics of TCM syndrome elements,and provide reference for early intervention,di-agnosis and treatment of COPD.Methods:From May 2022 to November 2022,a cross-sectional study of high-risk COPD population was conducted in some areas of Anhui Province to extract disease location and disease syndrome elements from clinical manifestations.SPSS 21.0 software was used to analyze the symptoms and syndrome elements respectively by fre-quency analysis and cluster analysis.Results:A total of 734 subjects with high risk of COPD were included.Cough,expec-toration,forgetfulness,soreness and weakness of waist and knees,dry mouth and bitter mouth,shortness of breath and fa-tigue were the high frequency symptoms.34.74%of the high-risk population suffered from respiratory system diseases,in-cluding chronic bronchitis,allergic rhinitis,bronchial asthma,pharyngitis,emphysema,pulmonary bullae,pulmonary nodules,etc.Syndrome elements analysis of 734 patients with high risk of COPD were conducted.7 syndrome elements of disease location and 10 syndrome elements of disease nature were obtained.The descending order of disease location syn-drome elements was lung(49.59%),kidney(28.20%),spleen(26.70%),liver(17.44%),defensive surface(12.81%),heart spirit(7.36%),and stomach(6.95%).The descending order of disease nature syndrome elements was Qi deficiency(53.00%),phlegm(26.3%),dampness(13.22%),Yin deficiency(11.58%),Yang deficiency(11.44%),heat(10.63%),blood stasis(4.77%),etc.Six combination rules were found by cluster analysis:(1)disease location syndrome elements lung,spleen,stomach + disease nature syndrome elements phlegm,Qi deficiency and dampness;(2)disease lo-cation syndrome element kidney + disease nature syndrome elements Yin deficiency and Yang deficiency;(3)disease loca-tion syndrome element blood stasis;(4)disease location syndrome element liver + disease nature syndrome elements hyper-activity of Yang,heat and Qi stagnation;(5)disease location syndrome element heart(spirit);(6)disease location syn-drome element defensive surface.Conclusion:People with high risk of COPD have the manifestations of lung-Qi deficiency before they develop into COPD.The development of COPD begins with lung-Qi deficiency,further damages to the spleen and kidney,and gradually evolves into the intermingled deficiency and excess.
high-risk COPD populationclinical symptomsdisease nature syndrome elementdisease location syn-drome element
NETL
NSTL
万方数据
维普
