Clinical observation of Yiqi Huoxue Formula in the treatment of atrophic gastritis with intesti-nal metaplasia
Objective:To observe the clinical efficacy of Yiqi Huoxue Formula in the treatment of chronic atrophic(CAG)gastritis with intestinal metaplasia(IM).Methods:The general data of 30 CAG patients with IM with syndrome of Qi deficiency and blood stasis diagnosed and treated in Maternal and Child Health Care Hospital of Zibo from July 2021 to July 2022 were retrospectively analyzed.All patients were treated with modified Yiqi Huoxue Formula.Results:Compared with those before treatment,the scores of gastric mucosa tissue,including congestion and edema,red alternating with white,bile reflux,vascular network exposure,gastric gland atrophy,intestinal metaplasia,dysplasia,and TCM syndrome scores were decreased after treatment.The levels of PGⅠ,PGⅡ,G-17 and MOT increased,the differences were statisti-cally significant(P<0.05).The eradication rate of Helicobacter pylori(Hp)was 90.00%(27/30),and no adverse reactions such as abnormal liver and kidney function were observed.Conclusion:Yiqi Huoxue Formula is effective in the treatment of CAG with IM,which can improve the symptoms and signs of patients,promote Hp eradication,and has high safety.It is worthy of clinical application.
atrophic gastritisintestinal metaplasiaYiqi Huoxue Formula