首页|柴胡疏肝散加减联合黛力新治疗肝郁脾虚型功能性消化不良疗效观察

柴胡疏肝散加减联合黛力新治疗肝郁脾虚型功能性消化不良疗效观察

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目的:探究在肝郁脾虚型功能性消化不良治疗中应用柴胡疏肝散加减联合黛力新的临床效果.方法:纳入2019年10月—2020年10月于甘肃省敦煌市医院慢病门诊就诊的肝郁脾虚型功能性消化不良患者84例,随机分为对照组(黛力新)和研究组(柴胡疏肝散加减+黛力新),每组42例.比较两组患者临床疗效、治疗前后中医证候积分、焦虑抑郁评分及改善率、胃肠功能恢复时间、临床症状消失时间、不良反应发生率等指标.结果:研究组较对照组治疗总有效率更高,差异有统计学意义(P<0.05);治疗后两组患者腹部不适、腹胀、嗳气症状积分及HAMD、HAMA评分均降低(P<0.05),上述指标研究组较对照组更低(P<0.01),差异均有统计学意义;研究组胃肠功能恢复时间、临床症状消失时间更短,差异有统计学意义(P<0.01);两组不良反应发生率比较,差异无统计学意义(P>0.05),经对症干预后不良反应完全消失.结论:肝郁脾虚型功能性消化不良患者应用柴胡疏肝散加减联合黛力新治疗,可发挥显著的临床疗效,促进患者症状改善,且用药安全性高.
Clinical observation of modified Chaihu Shugan Powder combined with Deanxit in the treat-ment of functional dyspepsia with liver stagnation and spleen deficiency syndrome
Objective:To explore the clinical effect of modified Chaihu Shugan Powder combined with Deanxit in the treatment of functional dyspepsia with liver stagnation and spleen deficiency syndrome.Methods:A total of 84 patients with functional dyspepsia with liver stagnation and spleen deficiency syndrome who were treated in the chronic disease clinic of Dunhuang Hospital in Gansu Province from October 2019 to October 2020 were randomly divided into the control group(Deanxit)and the study group(Chaihu Shugan Powder+Deanxit),with 42 cases in each group.The clinical efficacy,TCM syndrome scores before and after treatment,anxiety and depression score,improvement rate,recovery time of gastrointesti-nal function,disappearance time of clinical symptoms,and incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the symptom scores of abdominal discomfort,abdominal distension and belching,HAMD and HAMA scores decreased in both groups(P<0.05).The above indexes in the study group were lower than those in the control group,and the differences were statistically significant(P<0.01).The recovery time of gastrointes-tinal function and the disappearance time of clinical symptoms in the study group were shorter than those in the control group,and the difference was statistically significant(P<0.01).There was no statistical significance in the incidence of ad-verse reactions between the two groups(P>0.05).It disappeared completely after symptomatic intervention.Conclusion:The application of modified Chaihu Shugan Powder combined with Deanxit in the treatment of functional dyspepsia with liver stagnation and spleen deficiency syndrome can play a significant clinical effect,promote the improvement of patients'symptoms,and has high drug safety.

functional dyspepsiamodified Chaihu Shugan PowderDeanxitliver stagnation and spleen deficiency syndrome

冶兆军、王晓红

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甘肃省敦煌市医院消化肿瘤科,甘肃 敦煌 736200

甘肃省敦煌市中医医院肛肠科,甘肃 敦煌 736200

功能性消化不良 柴胡疏肝散加减 黛力新 肝郁脾虚型

2024

山西中医药大学学报

山西中医药大学学报

ISSN:
年,卷(期):2024.25(2)
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