首页|不同产地黄芪的多指标质量评价研究

不同产地黄芪的多指标质量评价研究

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目的:对12个不同产地的黄芪样品的质量进行评价.方法:以总多糖、总黄酮、总皂苷、毛蕊异黄酮葡萄糖苷、毛蕊异黄酮、芒柄花素、芒柄花苷及黄芪甲苷8个指标对甘肃、山西、内蒙古及宁夏等产地的12个黄芪样品进行多维分析,并考察8个指标的相关性.结果:12个样品中有3个样品的毛蕊异黄酮葡萄糖苷含量以及8个样品的黄芪甲苷含量不符合《中华人民共和国药典》(2020年版)规定要求.12个不同产地的黄芪样品中总多糖、总黄酮、总皂苷、毛蕊异黄酮葡萄糖苷、毛蕊异黄酮、芒柄花素、芒柄花苷及黄芪甲苷等8个指标的含量(mg/g)分别为13.389~68.777、3.132~4.408、6.761~18.284、0.143~0.374、0.023~0.169、0.020~0.119、0.044~0.110、0.051~1.399 mg/g.芒柄花苷含量与毛蕊异黄酮葡萄糖苷含量呈正相关(r=0.838),芒柄花素含量与毛蕊异黄酮含量呈正相关(r=0.973),黄芪甲苷含量与其他7个指标含量无相关性.结论:不同产地黄芪的化学成分含量差异显著,质量差异明显,选购黄芪药材需注意其直径的大小.
Study on multi-index quality evaluation of Huangqi from different producing areas
Objective:To evaluate the quality of Huangqi samples from 12 different producing areas.Methods:12 Huangqi samples from Gansu,Shanxi,Inner Mongolia and Ningxia were multidimensionally analyzed with 8 indexes,in-cluding total polysaccharide,total flavones,total saponins,calycosin-7-O-β-D-glucoside,calycosin,formononetin,ononin and astragaloside,and the correlation of 8 indexes was investigated.Results:The calycosin-7-O-β-D-glucoside content of 3 samples and the astragaloside content of 8 samples did not meet the requirements stipulated in the Pharmaco-poeia of the People's Republic of China(2020 edition).The contents(mg/g)of total polysaccharide,total flavones,total sa-ponins,calycosin-7-O-β-D-glucoside,calycosin,formononetin,ononin and astragaloside in Huangqi samples from 12 different producing areas were 13.389~68.777,3.132~4.408,6.761~18.284.0.143~0.374,0.023~0.169,0.020~0.119,0.044~0.110,and 0.051~1.399 mg/g,respectively.There was a positive correlation between the content of ononin and the content of calycosin-7-O-β-D-glucoside(r=0.838),and the content of formononetin and the content of calycosin(r=0.973).There was no correlation between the content of astragaloside and the other 7 indexes.Conclusion:The chemical content and quality of Huangqi from different producing areas are significantly different,so it is necessary to pay attention to its diameter when purchasing Huangqi herbs.

Huangqiastragalosidecalycosin-7-O-β-D-glucosidecorrelation analysisproducing areasevapora-tive light scattering

高伟城、王小平、李鑫如、莫文雯、陈荣珠、李珍、林少芬

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漳州卫生职业学院药学院,福建 漳州 363000

漳州市聚善堂药业有限公司,福建 漳州 363007

黄芪 黄芪甲苷 毛蕊异黄酮葡萄糖苷 相关性分析 产地 蒸发光散射

第三批国家级职业教育教师创新团队项目宁夏海原黄芪药用及食用品质研究项目漳州卫生职业学院科技创新团队培育计划项目

教师函[2023]9ZWYMN202301kjcx-5

2024

山西中医药大学学报

山西中医药大学学报

ISSN:
年,卷(期):2024.25(5)
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