基于气络-NEI网络共性特征探析痫证治法

Based on the common characteristics of Qi Luo-NEI network,the treatment of epilepsy is explored and analyzed

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中文摘要：神经-内分泌-免疫网络(NEI)是近年医学生物学的研究热点,即神经、内分泌、免疫三大系统之间存在着互相调节、互相影响的关系.气络是人体内运行经气的网络,是维持生命活动和保持人体内环境稳定的网络结构.气络-NEI网络具有高度相关性,功能上、结构上都存在共性特征.痫证与气络-NEI网络调节失衡有关.结合气络学说,痫证基本病机特点为虚(正虚、气虚、肾虚)、瘀血、痰浊、毒,主张以益气、化瘀、解毒法为主要治则.痫证迁延不愈,与正气不足,脏腑失调,痰浊瘀血,毒损脑络有关.故在治法上宜结合气络-NEI网络共性特征,以益气、祛瘀、化瘀、解毒法为主要治则,对于深化痫证病机认识及络病学说有一定积极意义.本研究对痫证的临床诊疗和研究络病理论研究具有重要价值.

外文摘要：In recent years,the neuro-endocrine-immune(NEI)network has emerged as a prominent research focus within the field of medical biology.This network signifies the interrelated mechanisms of mutual regulation and influence among the nervous,endocrine,and immune systems.The Qi-luo is a network of qi that operates within the human body,which maintains the stability of life activities and the internal environment of the human body.The Qi-luo and NEI networks exhibit a high degree of correlation and share commonalities in both functional and structural aspects.The pathophysiology of epilepsy is associated with the dysregulation of the Qi-luo and NEI networks.According to the theory of Qi-luo,the basic pathological mechanism of epilepsy is deficiency(deficiency of health,qi deficiency,kidney deficiency),blood stasis,phlegm and toxicity.It is advocated to give priority to replenishing qi,activating blood,and detoxicating.Epilepsy that lasts long and doesn't cure is related to the deficiency of vital energy,imbalance of organs,blood stasis,phlegm and brain dam-age due to toxicity.Therefore,in the treatment,it is advisable to combine the common characteristics of Qi-luo and NEI network,and take replenishing qi,activating blood and detoxicating as the main principles.It has certain positive signifi-cance for deepening the understanding of epilepsy pathogenesis and the theory of collaterals disease.This study has impor-tant value for the clinical diagnosis and treatment of epilepsy and the theoretical research of collaterals disease.

外文关键词：

epilepsyneuro immune endocrine networkcollateral diseasetraditional Chinese medicine

作者：

张林、张艳菊、杨辉、何晓芳

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作者单位：

贵州中医药大学第二附属医院,贵州贵阳 550003

贵州省人民医院,贵州贵阳 550003

关键词：

痫证神经-免疫-内分泌网络络病中医

基金：

国家自然科学基金贵州省科技计划项目贵州省中医药、民族医药科学技术研究专项课题贵州中医药大学校级课题贵州中医药大学第二附属医院院内项目

项目编号：

82060863黔科合基础-ZK[2021]一般500QZYY-2024-068贵中医科院内[2019]20GZEYK[2020]11

出版年：

2024

DOI：

10.19763/j.cnki.2096-7403.2024.07.15

山西中医药大学学报

ISSN：

年,卷(期)：2024.25(7)