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针刺治疗卵巢储备功能下降选穴规律探讨

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目的:运用数据挖掘技术分析针刺治疗卵巢储备功能下降(DOR)的选穴规律.方法:计算机检索中国知网、万方、维普、PubMed、Web of Science数据库自建库至2023年11月31日收录的针刺治疗DOR的相关文献.使用Excel 365建立数据库,统计腧穴使用频次、归经、特定穴归属、干预方案,分别使用IBM SPSS Modeler 18.0、Cytoscape 3.9.1、IBM SPSS Statistics 26.0对腧穴进行关联规则、共现网络、聚类分析.结果:共纳入文献56篇,涉及针刺处方76条,腧穴60个,高频腧穴为关元、三阴交、足三里等,核心穴组为关元-三阴交,常用经脉为任脉、脾经、胃经、膀胱经、肾经,特定穴常用交会穴、五输穴、募穴.聚类分析得到2个有效聚类,聚类1:气海、关元、大赫、足三里、归来、中极;聚类2:血海、子宫、太冲、太溪、三阴交、肾俞、次髎、百会.干预方案以电针+中药应用最多,针刺+中药总有效率最高.结论:针刺治疗DOR以局部取穴和特定穴为主,注重冲任、肾脾肝同调,临床常与中药内服、艾灸、刺络拔罐、穴位贴敷、穴位埋线等其他疗法联合应用.
Discussion on the acupoint selection patterns in acupuncture treatment for declined ovarian reserve
Objective:To analyze the acupoint selection patterns in acupuncture treatment for declined ovarian reserve(DOR)using data mining techniques.Methods:We conducted a computerized search of CNKI,Wanfang,VIP,PubMed,and Web of Science databases from their inception to November 31,2023,for articles related to acupuncture treatment for DOR.An Excel 365 database was established to collect data on acupoint frequency,meridian attribution,specific acupoint classification,and intervention protocols.IBM SPSS Modeler 18.0,Cytoscape 3.9.1,and IBM SPSS Statistics 26.0 were used for association rule analysis,co-occurrence network analysis,and cluster analysis of acupoints,respectively.Re-sults:A total of 56 articles were included,covering 76 acupuncture prescriptions and 60 acupoints.The most frequently used acupoints were Guanyuan,Sanyinjiao,and Zusanli.The core acupoint combination was Guanyuan-Sanyinjiao.The most commonly used meridians were the conception vessel,spleen meridian,stomach meridian,bladder meridian,and kidney meridian.Specific acupoints frequently used included confluent points,five-shu points,and front-mu points.Clus-ter analysis yielded two effective clusters:Cluster 1 included Qihai,Guanyuan,Daheng,Zusanli,Guilai,and Zhongji;Cluster 2 included Xuehai,Zigong,Taichong,Taixi,Sanyinjiao,Shenshu,Ciliao,and Baihui.The most common inter-vention protocol was electroacupuncture combined with Chinese medicine,and acupuncture plus Chinese medicine had the highest overall effectiveness rate.Conclusion:Acupuncture treatment for DOR is based on localized acupuncture points and specific points,focusing on Chong Ren,kidney,spleen and liver co-regulation,and is often combined with other therapies such as internal administration of Chinese medicine,moxibustion,puncture and cupping,acupoint plastering and acupoint catgut embedding.

declined ovarian reserveacupuncturedata miningacupoint selection patternliterature research

代紫莹、孙建华、郭本婕、卡丽比努尔·依马木、陈银燕、裴丽霞

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南京中医药大学附属医院,江苏 南京 213161

卵巢储备功能下降 针刺 数据挖掘 选穴规律 文献研究

国家自然基金面上项目江苏省中医院高峰人才项目江苏省中医院高峰人才项目

82174489y2021rc04y2021rc50

2024

山西中医药大学学报

山西中医药大学学报

ISSN:
年,卷(期):2024.25(8)