Clinical study of Sangju Xunan Formula combined with meibomian gland massage in the treatment of dry eyes caused by stagnated heat of liver channel after SMILE surgery
Objective:To explore the effect of Chinese herb Sangju Xunan Formula combined with meibomian gland massage for dry eyes caused by stagnated heat of liver channel after SMILE surgery.Methods:60 patients(120 eyes)diag-nosed as dry eyes caused by stagnated heat of liver channel after syndrome differentiation of TCM after 2 weeks of SMILE surgery who received treatment in Eye Hospital of Dongguan Huaxia from May 2023 to December 2023 were selected,and were randomly divided into control group and research group according to random number table method.30 patients(60 eyes)in the control group were given sodium hyaluronate eye drops and flumiron eye drops,and 30 patients(60 eyes)in the research group were given ultrasonic atomization fumigation with self-designed Sangju Xunan Formula and meibomian gland massage on the treatment basis of the control group.Patients in both groups were treated for 30 days.Before and after treatment,the uncorrected visual acuity,ocular surface disease index(OSDI)scale score,TCM symptom score,Schirmer Ⅰ test,tear film break-up time(NIBUT),height of the tear river,corneal fluorescein sodium staining(CFS)score and adverse reactions were recorded and compared between the two groups.Results:There was no significant difference in the above indicators between the two groups before treatment(P>0.05).After treatment,the above indexes of the two groups were improved,and the indexes of the research group were better than those of the control group,with the statistical differ-ences(P<0.05,P<0.01).The total effective rate of the research group(90.00%)was higher than that of the control group(70.00%),and the difference was statistically significant(P<0.01).During the treatment,no adverse reactions occurred in the two groups.Conclusion:The combination of Sangju Xunan Formula and meibomian gland massage has a good clinical efficacy in the treatment of dry eyes caused by stagnated heat of liver channel after SMILE surgery.It can significantly im-prove the symptoms of eye discomfort,improve the uncorrected visual acuity,prolong the tear film break-up time,promote tear secretion,and stabilize the tear film,which is worthy of clinical application.