With the development of science and technology,the application of new technology in medical examination is more and more extensive.Compared with the complicated and time-consuming workflow of traditional microbial identification,matrix-assisted laser desorption ionization time-of-flight mass spectrometry(MALDI-TOF MS)has gradually become an indispensable microbial identification tool in clinical microbiological laboratories because of its rapid,sensitivity,simple,time-saving and high specificity.MALDI-TOF MS plays a role in isolate identification,drug resistance monitoring and mutation identification.Its identification relies on the database,and it is limited to a certain extent by the quality of clinical samples.MALDI-TOF MS will still have utilization space to be developed in clinical microbiological examination.
Matrix-assisted laser desorption ionization time-of-flight mass spectrometryRapid identificationDatabaseDrug resistance monitoring
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