Histones are the main protein components of chromatin and play roles in the regulation of biological genetic information.As a common product of cell metabolism,lactic acid can affect the expression of cell genetic information.Under the action of related enzymes,histones can undergo chemical modifications of various groups,among which lactation is one of the important chemical modifications.This review mainly focuses on the occurrence and influencing factors of histone lactation,the relationship between histone lactation and common diseases and the research progress of treatment.
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