Objective:To explore the application value of contrast-enhanced ultrasound(CEUS)-computed tomography(CT)/magnetic resonance imaging(MRI)fusion image virtual navigation in the biopsy of diffuse liver carcinoma.Methods:Patients with diffuse liver carcinoma detected by contrast-enhanced CT/MRI but not detected by conventional ultrasound in Nanjing Drum Tower Hospital were collected.The images of ultrasound and contrast-enhanced CT/MRI were fused by fusion imaging technology,and then CEUS was performed.The conventional ultrasound,CEUS,CT/MRI images and the visibility of the lesions were observed and analyzed.All patients underwent percutaneous liver biopsy under virtual navigation,and the success rate of puncture was summarized.Results:CEUS-CT/MRI fusion imaging was completed in all 21 cases,and the success rate of fusion was 100.0%.Under conventional ultrasound,none of the 21 cases could be displayed.In CEUS mode,66.7%(14/21)of the lesions were displayed in the arterial phase and 47.6%(10/21)in the delayed phase.Twenty-three percutaneous liver biopsies were performed under the guidance of virtual navigation.The positive rate of the first localization biopsy was 90.5%(19/21),and 2 false negative cases obtained positive pathological results in the second biopsy.Conclusion:Fusion image-guided virtual navigation technology has a high value in the localization and qualitative diagnosis of diffuse liver carcinoma which is difficult to display by conventional ultrasound.
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