Effect of Bu Shen An Shen needling method on endometrial receptivity in patients with early recurrent spontaneous abortion:a randomized controlled study
Objective To observe the effects of Bu Shen An Shen needling method on the peak systolic velocity/end diastolic velocity(S/D)of uterine arteries,endometrial thickness,and pregnancy outcomes in patients with early recurrent spontaneous abortion(eRSA).Method A total of 154 eRSA patients were randomized into an observation group and a control group,with 77 cases in each group.In addition to individualized treatments,the observation group received Bu Shen An Shen needling method,and the control group received subcutaneous injections of low-molecular-weight Heparin.Before and after the treatment,the transvaginal color Doppler ultrasound was used to detect the uterine artery S/D and endometrial thickness in the mid-luteal phase.The pregnancy preparation time and clinical efficacy were also compared between the two groups.Result After the treatment,the uterine artery S/D improved in each group(P＜0.05),but the between-group difference was statistically insignificant(P＞0.05).Among those whose endometrial thickness was≤7 mm at the baseline,their endometrial thickness increased after the treatment,and the observation group surpassed the control group,showing statistical significance(P＜0.05).Among those whose endometrial thickness was＞7 mm at the baseline,their endometrial thickness did not show significant changes after the treatment,and the between-group difference was statistically insignificant(P＞0.05).The observation group had a shorter pregnancy preparation time than the control group(P＜0.05).The pregnancy rate was 89.6% in the observation group versus 88.3% in the control group,and the between-group difference was statistically insignificant(P＞0.05).Conclusion Based on individualized treatments in treating eRSA patients,Bu Shen An Shen needling method can reduce the blood flow resistance of the uterine artery and increase endometrial thickness to improve endometrial receptivity,shorten pregnancy preparation time,and increase birth rate.
万方数据
维普
