Effect of short-term acupuncture-moxibustion intervention on the pregnancy outcome in people undergoing frozen-thawed embryo transfer
Objective To observe the effect of short-term acupuncture-moxibustion intervention on the pregnancy outcome in patients undergoing frozen-thawed embryo transfer(FET)by retrospectively analyzing 694 FET cycles.Method The 694 FET cycles were divided into an observation group(301 cycles)and a control group(393 cycles).The control group received conventional FET.The observation group received acupuncture-moxibustion for 5-6 d starting from the day of endometrial transformation.Baseline data(age,number of previous cycles,years of infertility,luteinizing hormone level at the basal day,follicular estrogen level at the basal day,estradiol level at the basal day,body mass index,number of embryo transfers,endometrial thickness on the day of transfer,type of infertility)were collected from both groups to explore risk factors for pregnancy outcomes in infertile patients receiving FET treatment using the single-factor and multivariate logistic regression.The embryo implantation rate,early miscarriage rate,and clinical efficacy were compared between the two groups.Result The observation group had a higher clinical pregnancy rate than the control group,46.5% versus 39.4%,showing statistical significance(P＜0.01).The embryo implantation rate was 33.5% in the observation group,significantly higher than 25.9% in the control group(P＜0.05).The early miscarriage rate in the observation group(12.9% )was lower than that in the control group(22.0% ),and the difference was statistically significant(P＜0.05).Acupuncture-moxibustion and age were factors that affected the pregnancy outcome(P＜0.05).Conclusion Incorporating acupuncture-moxibustion into FET can enhance the clinical pregnancy rate and embryo implantation rate and reduce the early miscarriage rate in patients undergoing FET.
万方数据
维普
