Therapeutic observation of medicinal thread moxibustion combined with Zhuang medication for cervicitis complicated with persistent human papillomavirus infection
Objective To observe the clinical efficacy using Zhuang medicine's medicinal thread moxibustion and Qing Du formula in treating cervicitis complicated with persistent high-risk human papillomavirus(HR-HPV)infection.Method Fifty-nine eligible participants with cervicitis complicated with persistent HR-HPV infection were randomly divided into an observation group(29 cases)and a control group(30 cases).The observation group was treated with Zhuang medicine's medicinal thread moxibustion plus Qing Du formula via oral administration.The control group was treated with anti-HPV β-glucan functional dressing through posterior vaginal fornix.Before and after the treatment,both groups were observed for changes in the symptoms of Zhuang medicine,HPV load,and serum levels of interleukin-6(IL-6)and C-reactive protein(CRP).The clinical efficacy was compared between the two groups,and the adverse reactions were observed.Result After the treatment,the observation group was superior to the control group in comparing the incidence rate of symptoms of Zhuang medicine,healing time of cervical erosion,and HPV load difference(P＜0.05).The serum levels of CRP and IL-6 dropped in each group after the intervention(P＜0.05),but the between-group differences were statistically insignificant(P＞0.05).The cervical erosion recovery rate and the total effective rate of HPV infection were higher in the observation group than in the control group(P＜0.05).The observation group had a lower adverse reaction rate than the control group(P＜0.05).Conclusion For cervicitis complicated with persistent HR-HPV infection,Zhuang medicine's medicinal thread moxibustion plus Qing Du formula can effectively eradicate the HPV virus,lower HPV load,promote the healing of cervical erosion,shorten the time for recovery,and down-regulate inflammatory indicators,with a satisfactory safety rating.
Zhuang thread moxibustionZhuang drugsCervicitisHuman papillomavirus virusesChuang medicineinterleukin-6C-reactive protein
万方数据
维普
