Clinical observation of acupuncture combined with heat-sensitive moxibustion in the treatment of post-stroke cognitive impairment
Objective To observe the clinical efficacy of"San Tong Xing Nao acupuncture"combined with heat-sensitive moxibustion in the treatment of post-stroke cognitive impairment(PSCI).Method Ninety patients with PSCI were randomly divided into the acupuncture group,the thermal moxibustion group and the combined group,with 30 cases in each group.Patients in each of the three groups were treated with conventional internal medicine and rehabilitation,based on which,the acupuncture group was treated with"San Tong Xing Nao"acupuncture,the heat-sensitive moxibustion group was treated with heat-sensitive moxibustion,and the combined group was treated with"San Tong Xing Nao"acupuncture combined with heat-sensitive moxibustion.The mini-mental state examination(MMSE),Montreal cognitive assessment(MoCA),modified Barthel index(MBI)score,amplitude and latency of auditory event-related potential P300,and changes in serum homocysteine(Hcy)and interleukin-6(IL-6)levels were observed in the three groups before and after treatment.Result The MoCA,MMSE and MBI scores of the three groups were higher than those before treatment,and those in the combined group were higher than those in the acupuncture and heat-sensitive moxibustion groups,with statistically significant differences(P<0.05).The P300 latency of the combined group was shorter than that of the acupuncture group and heat-sensitive moxibustion group,and the amplitude of P300 in the combined group was longer than that in the acupuncture and heat-sensitive moxibustion groups;the differences were statistically significant(P<0.05).Serum Hcy and IL-6 levels were reduced in the three groups after treatment,and those in the combined group was lower than those in the acupuncture and heat-sensitive moxibustion groups;the difference was statistically significant(P<0.05).Conclusion The combination of heat-sensitive moxibustion with"San Tong Xing Nao acupuncture"on the basis of conventional internal medicine and rehabilitation treatment can help to improve the cognitive function and daily life ability of PSCI patients.