Therapeutic efficacy of Bo's abdominal acupuncture combined with Chinese herbal medicines in the treatment of infertility evidence of varicocele
Objective To observe the clinical efficacy of Bo's Abdominal Acupuncture combined with Yi Kidney Tongluo Formula in the treatment of varicocele infertility with kidney deficiency induced blood stasis pattern,and its effect on semen quality and sperm DNA fragmentation index(DFI).Method A total of 102 patients with varicocele infertility of kidney deficiency induced blood stasis pattern were selected and randomly divided into the control group and the observation group,with 51 cases in each group.The control group was treated with Yishen-Tongluo formula,while the observation group was treated with Bo's abdominal acupuncture on the basis of the control group.Before and after the treatment,the Chinese medicine syndrome score,vascular diameter of the spermatic vein,semen quality[sperm concentration,sperm progressive(PR)﹢ non-progressive(NP)rate,sperm PR rate],sperm DFI and sex hormones of semen[follicle-stimulating hormone(FSH),luteinizing hormone(LH)and testosterone(T)]were compared,and the clinical efficacy and the occurrence of adverse effects were also compared between the two groups.Result The total effective rate of the observation group was 94.1%,which was higher than 76.5% of the control group(P＜0.05).After treatment,the Chinese medicine syndrome scores and the diameter of spermatic vein vessels of both groups were lower than those before treatment(P＜0.05);the Chinese medicine syndrome scores and the diameter of spermatic vein vessels of the observation group were lower than those of the control group after treatment(P＜0.05).Sperm concentration,PR﹢NP rate and PR rate increased after treatment in both groups compared with that before treatment(P＜0.05),and DFI decreased compared with that before treatment(P＜0.05);sperm concentration,PR﹢NP and PR in the observation group were higher than that in the control group after treatment(P＜0.05),and DFI in the observation group was lower than that in the control group(P＜0.05).The levels of FSH and LH of both groups after treatment were lower than those before treatment(P＜0.05),and the level of T was higher than that before treatment(P＜0.05);the levels of FSH and LH of the observation group after treatment were lower than that of the control group(P＜0.05),and the level of T of the observation group was higher than that of the control group(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion Bo's abdominal acupuncture combined with Yishen-Tongluo formula can regulate the secretion of sex hormones,improve the quality of semen,and significantly improve the clinical symptoms in patients with varicocele infertility due to kidney deficiency induced blood stasis.
Acupuncture therapyAcupuncture-medication combinedInfertility,maleAbdominal acupunctureKidney deficiency and blood stagnationVaricocele
万方数据
维普
