上海中医药大学学报2024,Vol.38Issue(1) :18-26.DOI:10.16306/j.1008-861x.2024.01.003

基于"辨状论质"的地域性市售丹参饮片质量等级评价研究

Study on quality grade evaluation of Salvia miltiorrhiza decoction pieces sold in regional market based on"quality evaluation through morphological identification"

冯昊 陈俊源 黄豆豆 杨颖博 肖莹 陈万生 孙连娜
上海中医药大学学报2024,Vol.38Issue(1) :18-26.DOI:10.16306/j.1008-861x.2024.01.003

基于"辨状论质"的地域性市售丹参饮片质量等级评价研究

Study on quality grade evaluation of Salvia miltiorrhiza decoction pieces sold in regional market based on"quality evaluation through morphological identification"

冯昊 1陈俊源 1黄豆豆 1杨颖博 2肖莹 3陈万生 3孙连娜1
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作者信息

  • 1. 上海中医药大学中药学院(上海 201203)
  • 2. 上海中医药大学中药研究所(上海 201203);江苏康缘药业股份有限公司(江苏 连云港 222001)
  • 3. 上海中医药大学中药研究所(上海 201203)
  • 折叠

摘要

目的:考察丹参饮片性状指标与内在成分含量的相关性,筛选获得可行可控的质控指标,建立科学合理的地域性市售丹参饮片等级标准.方法:基于"辨状论质"理论,将来源于上海市售的不同直径和不同切面颜色丹参饮片分等,采用色差仪对不同切面颜色丹参饮片粉末颜色值进行测量,结合饮片指标性化学成分含量,使用OriginLab 2021软件进行Pearson相关性分析.结果:丹参饮片直径与总丹参酮和丹参酮Ⅱ A含量呈极显著负相关,与丹酚酸含量呈极显著正相关;丹参饮片切面颜色与粉末L值呈极显著负相关.丹参饮片粉末L值与丹酚酸B含量呈极显著正相关,b值与丹酚酸B含量呈极显著负相关.结论:丹参饮片直径和切面颜色指标可作为其内在品质判断指标,为上海地区市售丹参饮片等级标准提供客观、科学的理论依据.

Abstract

Objective:To investigate the correlation between the character indexes of Salvia miltiorrhiza decoction pieces and the content of internal components,screen out feasible and controllable quality control indexes,and establish a scientific and reasonable grade standard of Salvia miltiorrhiza decoction pieces sold in regional market.Method:Based on the theory of"quality evaluation through morphological identification",the Salvia miltiorrhiza decoction pieces sold in Shanghai with different diameters and different section colors were classified.A color meter was used to measure powder color values of Salvia miltiorrhiza decoction pieces with different section colors.Combined with the content of index chemical components of decoction pieces,Pearson correlation analysis was performed by OriginLab 2021 software.Results:The diameter of Salvia miltiorrhiza decoction pieces were significantly negatively correlated with the content of total tanshinone and tanshinone ⅡA,and was highly significantly positively correlated with the contents of salvianolic acid.There was a highly significant negative correlation between the section color of Salvia miltiorrhiza decoction pieces and the L value of its powder.The L value of Salvia miltiorrhiza decoction pieces powder was highly significantly positively correlated with the content of salvianolic acid B,and the b value was highly significantly negatively correlated with the content of salvianolic acid B.Conclusion:The diameter and section color of Salvia miltiorrhiza decoction pieces can be used as the internal quality judgment indexes,which provides an objective and scientific theoretical basis for the grade standard of Salvia miltiorrhiza decoction pieces sold in Shanghai.

关键词

丹参饮片/直径/切面颜色/相关性分析

Key words

Salvia miltiorrhiza decoction pieces/diameter/section color/correlation analysis

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基金项目

上海市进一步加快中医药传承创新发展三年行动计划项目(ZY[2021-2023]-0215)

出版年

2024
上海中医药大学学报
上海中医药大学,上海市中医药研究院

上海中医药大学学报

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影响因子:0.788
ISSN:1008-861X
参考文献量21
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