首页|薏苡附子败酱散干预结肠"炎-癌"转化的研究概况

薏苡附子败酱散干预结肠"炎-癌"转化的研究概况

扫码查看
结肠"炎-癌"转化是指炎症性肠病逐步向结直肠癌(CRC)发展的过程.虚-湿-毒与CRC发生发展密切相关,虚-湿-毒影响肿瘤微环境促进肿瘤生长,同时也是结肠"炎-癌"转化的重要病因病机.薏苡附子败酱散具有祛湿解毒消痈、补虚助阳驱邪之功,可延缓因虚-湿-毒引起的结肠"炎-癌"转化的进程.故课题组对结肠"炎-癌"转化、肿瘤微环境的作用、中医对结肠"炎-癌"转化的认识,特别是薏苡附子败酱散干预结肠"炎-癌"转化的过程进行评述,以期为其治疗结肠相关疾病提供新思路.
Research progress on intervention of Yiyi Fuzi Baijiang Powder in colitis-to-colorectal-cancer transformation
Colitis-to-colorectal-cancer transformation refers to the gradual development from inflammatory bowel disease into colorectal cancer(CRC)."Deficiency-dampness-toxin"is closely related to the occurrence and development of CRC."Deficiency-dampness-toxin"affects the microenvironment of tumor and promotes tumor growth,and it is also an important etiology and pathogenesis for the colitis-to-colorectal-cancer transformation.Yiyi Fuzi Baijiang Powder has the function of eliminating dampness,removing toxin and resolving abscess,tonifying deficiency,replenishing yang and removing pathogenic factors,which can delay the process of colitis-to-colon-cancer transformation caused by"deficiency-dampness-toxin".Therefore,the research group reviewed colitis-to-colorectal-cancer transformation,the role of tumor microenvironment,the understanding of Chinese medicine on colitis-to-colorectal-cancer transformation,especially the process of Yiyi Fuzi Baijiang Powder intervening in colitis-to-colon-cancer transformation,in order to provide new ideas for the treatment of colorectal-related diseases.

Yiyi Fuzi Baijiang Powdercolitiscolorectal cancerinflammation-cancer transformation

杨福芹、周晟、刘俊珊、周兴旺、邓丽娟

展开 >

暨南大学中医学院方证研究中心(广东 广州 510632)

南方医科大学中医药学院(广东 广州 510000)

中山大学中山医学院生化与分子生物学系(广东 广州 510275)

薏苡附子败酱散 结肠炎 结直肠癌 "炎-癌"转化

广东省自然科学基金青年提升项目广州市科技局基础研究计划一般项目广东省基础和应用基础研究基金

2023A15150302762022010114982019B1515120051

2024

上海中医药大学学报
上海中医药大学,上海市中医药研究院

上海中医药大学学报

CSTPCD
影响因子:0.788
ISSN:1008-861X
年,卷(期):2024.38(2)
  • 48