Objective:To observe the clinical effect of Dingxuan Shuyu Decoction in treating patients of hypertension combined with anxiety.Methods:A total of 74 patients of hypertension combined with anxiety with type of yin-deficiency and yang-hyperactivity,who were intolerance to anxiolytics,were included,and randomly divided into treatment group and a control group,37 cases in each group.The patients in both groups were given conventional antihypertensive drugs.Based on above,the patients in the treatment group were orally treated with Dingxuan Shuyu Formula,and the patients in the control group were orally treated with placebo,with a course of 4 weeks.Before and after treatment,the scores of Generalized Anxiety Disorder-7(GAD-7),Hamilton Anxiety Scale(HAMA)and self-rating sleep scale(SRSS),and the total scores of traditional Chinese Medicine syndrome in the two groups were evaluated and compared,and the levels of systolic and diastolic blood pressure of the patients in both groups were detected.Results:After treatment,the scores of GAD-7,HAMA and SRSS,and the total scores of traditional Chinese medicine syndrome in the treatment group were significantly decreased compared with those before treatment(P＜0.01),and were lower than those in the control group(P＜0.01).Meanwhile,the levels of systolic and diastolic blood pressure in the treatment group were also decreased compared with those before treatment(P＜0.05),and were lower than those in the control group(P＜0.05).Conclusion:Dingxuan Shuyu Formula has good clinical effect in the treatment of hypertension combined with anxiety.It can improve the anxiety and traditional Chinese medicine syndrome of the patients,and decrease the blood pressure,with good safety.
关键词
高血压/焦虑状态/失眠/定眩舒郁方/中西医结合
Key words
hypertension/anxiety state/insomnia/Dingxuan Shuyu Formula/integrated traditional Chinese and western medicine
维普
万方数据