Research progress on differences in chemical constituents and pharmacological activities between Lei Fang Kai-Xin-San and Ding-Zhi-Xiao-Wan
It is to review the differences in chemical constituents between Lei Fang Kai-Xin-San(KXS)and Ding-Zhi-Xiao-Wan(DZXW),and the research progress in pharmacological activities such as enhancing learning and memory,anti-oxidation,anti-depression and anti-Alzheimer disease(AD).The chemical constituents and pharmacological activities of KXS and DZXW were summerized by consulting the related literature.The results showed that the compatibility ratio of medicinal materials of DZXW was changed based on KXS,which led to the change of pharmacological activity.Both KXS and DZXW are widely used in anti-depression,anti-AD,improving learning and memory abilities,anti-aging and anti-fatigue,but their mechanisms are different.Some progress has been made in the study of chemical constituents and pharmacological activities of KXS and DZXW,however,scholars mostly conduct experiments based on basic models to prove the pharmacological effects of KXS and DZXW,but there is few research on the material basis of the efficacy and the mechanism of action,which needs further in-depth study.