Role of vascular endothelial growth factor signaling pathway in spinal cord injury and research progress on its traditional Chinese medicine intervention
Spinal cord injury is a serious neurological disease for which there is currently no effective treatment.The vascular endothelial growth factor(VEGF)signaling pathway plays an important role in spinal cord injury.It is involved in regulating processes such as angiogenesis,cell proliferation,and nerve regeneration.This article reviews the mechanism of VEGF signaling pathway in spinal cord injury and explores its important role in injury repair process.At the same time,a summary is made on the research progress of traditional Chinese medicine intervention in spinal cord injury.As a traditional treatment method,traditional Chinese medicine has unique advantages and has also achieved certain effects in the treatment of spinal cord injury.For example,traditional Chinese medicine as well as acupuncture and moxibustion can promote nerve regeneration and injury repair by regulating the VEGF signal pathway,providing new ideas and methods for the treatment of spinal cord injury.However,it also needs further basic research and clinical application to verify,in order to provide more effective methods and means for the treatment of spinal cord injury.
spinal cord injuryvascular endothelial growth factor(VEGF)angiogenesistraditional Chinese medicine therapy