世界科学技术-中医药现代化2024,Vol.26Issue(1) :242-251.DOI:10.11842/wst.20230127004

代谢综合征痰瘀互结证量化诊断标准的研究

Study on Quantitative Diagnostic Criteria of Phlegm-stasis Interjunction Syndrome of Metabolic Syndrome

刘亚丹 王斌 燕树勋 段飞
世界科学技术-中医药现代化2024,Vol.26Issue(1) :242-251.DOI:10.11842/wst.20230127004

代谢综合征痰瘀互结证量化诊断标准的研究

Study on Quantitative Diagnostic Criteria of Phlegm-stasis Interjunction Syndrome of Metabolic Syndrome

刘亚丹 1王斌 2燕树勋 3段飞3
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作者信息

  • 1. 河南中医药大学第一附属医院 郑州 450000;天津中医药大学第一附属医院 天津 300381;国家中医针灸临床医学研究中心 天津 300381
  • 2. 天津中医药大学第一附属医院 天津 300381;国家中医针灸临床医学研究中心 天津 300381
  • 3. 河南中医药大学第一附属医院 郑州 450000
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摘要

目的 确定代谢综合征痰瘀互结证量化诊断标准.方法 基于文献研究制定《基于层次分析法的MS痰瘀互结证专家咨询问卷》,邀请专家填写问卷,采用专家群决策算法构建《MS痰瘀互结证诊断标准(草案)》.前瞻性收集MS患者,采用条件概率换算法、最大似然判别法对MS痰瘀互结证诊断标准进行临床验证并修订,制定MS痰瘀互结证量化诊断标准.结果 建立的MS痰瘀互结证量化诊断标准诊断效能灵敏度95.7%,特异度84.0%,准确度91.6%,阳性似然比5.98,阴性似然比19.46.结论 基于文献研究、专家咨询法及诊断性试验建立的MS痰瘀互结证量化诊断标准具有较好的诊断效能.

Abstract

Objective To determine the quantitative diagnostic criteria of phlegm-stasis interjunction syndrome of metabolic syndrome.Methods Based on the literature research,the Expert Consultation Questionnaire for MS Syndrome of Phlegm-stasis Interjunction based on Analytic Hierarchy Process was developed.Experts were invited to fill out the questionnaire,and the Diagnostic Criteria for MS Syndrome of Phlegm-stasis Interjunction(Draft)was constructed by using the expert group decision algorithm.The patients with MS were prospectively collected,and the diagnostic criteria for phlegm-stasis interjunction syndrome of MS were validated and revised by conditional probability conversion method and maximum likelihood discrimination,and the quantitative diagnostic criteria for phlegm-stasis interjunction syndrome of MS were finally formulated.Results The sensitivity,specificity and accuracy of the established quantitative diagnostic criteria for MS phlegm-stasis interjunction syndrome were 95.7%,84.0%,91.6%,positive likelihood ratio 5.98,negative likelihood ratio 19.46.Conclusion The quantitative diagnostic criteria for MS phlegm-stasis interjunction syndrome established based on literature research,expert consultation and diagnostic tests have good diagnostic efficacy.

关键词

代谢综合征/痰瘀互结证/量化诊断标准/层次分析法

Key words

Metabolic syndrome/Phlegm-stasis interjunction syndrome/Quantitative diagnostic criteria/Analytic hierarchy process

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基金项目

河南省卫生健康委河南省中医药拔尖人才培养项目(第二批)(CZ0237-02)

河南省中医药传承与创新人才培养项目()

郑州市科技局郑州市科技惠民计划(2021KJHM0017)

出版年

2024
世界科学技术-中医药现代化
中科院科技政策与管理科学研究所,中国高技术产业发展促进会

世界科学技术-中医药现代化

CSTPCD北大核心
影响因子:1.175
ISSN:1674-3849
参考文献量33
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