On the Biological Basis of the Pathogenesis of Collaterals and Blood Stasis in IPF Based on the Abnormality of Pulmonary Capillary Permeability
In recent years,idiopathic pulmonary fibrosis has attracted much attention because of its high treatment cost,morbidity and mortality.Therefore,finding effective and low-cost treatment methods and drugs has become a difficult problem to be solved.The theory of collaterals disease has unique advantages in treating IPF.Based on the guidance of the theory of collateral disease,it is proposed that the pathogenesis of"collateral stasis"runs through the whole pathological stage of IPF,but its material basis is still unclear.In this article,through the in-depth study of the pathogenesis of idiopathic pulmonary fibrosis,the role of enhanced pulmonary capillary permeability and pulmonary vascular leakage in the pathological process of IPF was sorted out.Based on the theory of collateral disease,the biological basis of the pathogenesis of"collateral stasis"in IPF was further revealed,lays a foundation for the application of"gredging collaterals"therapy under the guidance of collateral disease theory,provides scientific basis for TCM treatment of IPF by collateral theory,and provides new ideas for TCM treatment of IPF.
NETL
NSTL
万方数据
