首页|铁皮石斛治疗糖尿病的药理机制研究进展

铁皮石斛治疗糖尿病的药理机制研究进展

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石斛是我国名贵中草药之一,铁皮石斛是中药石斛的上品,古代诸多医籍记载其具有治疗糖尿病的功效,作为"药食两用"的中药之一,铁皮石斛被广泛应用.现代药理研究表明,铁皮石斛具有抗肿瘤、抗疲劳、调节免疫、抗衰老以及降糖降脂的作用,在临床运用中,铁皮石斛同样具有平衡糖脂代谢、改善胰岛素抵抗、促进胰岛素分泌、提高胰岛细胞功能的作用,并具有一定的防治糖尿病并发症的作用.目前缺乏铁皮石斛治疗糖尿病的药理机制的系统综述,为更加全面了解现阶段铁皮石斛治疗糖尿病的药理作用,为进一步的药理研究提供参考依据,使其更好的应用于临床,故综述铁皮石斛防治糖尿病的药理作用机制研究进展.
Research Progress on the Pharmacological Mechanism of Dendrobium Officinale in the Treatment of Diabetes Mellitus
Dendrobium is one of the valuable Chinese herbs in China,and Dendrobium officinale is the top grade of Dendrobium,which is recorded in many ancient medical texts as having the efficacy of treating diabetes.Modern pharmacological research shows that Dendrobium has the effects of anti-tumor,anti-fatigue,immune regulation,anti-aging,and regulation of glycolipid metabolism.In clinical application,Dendrobium officinale also has the function of balancing glucose and lipid metabolism,improving insulin resistance,promoting insulin secretion,improving the function of islet cells,and has a certain role in the prevention and treatment of diabetic complications.At present,there is a lack of systematic review of the pharmacological mechanism of Dendrobium officinale in the treatment of diabetes.In order to understand the pharmacological action of Dendrobium officinale in the treatment of diabetes more comprehensively,and to provide a reference for further pharmacological research,so that it can be better applied in clinics,this paper reviews the research progress of the pharmacological mechanism of Dendrobium officinale in the treatment of diabetes.

Dendrobium officinaleDiabetes mellitusGlycolipid metabolismOxidative stressIntestinal flora

胡学芳、彭川、秦灵灵、吴丽丽、刘铜华

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成都中医药大学临床医学院 成都 610075

北京中医药大学中医养生学重点实验室 北京 100029

北京中医药大学科技处 北京 100029

铁皮石斛 糖尿病 糖脂代谢 氧化应激 肠道菌群

北京中医药大学横向课题

1130065120002

2024

世界科学技术-中医药现代化
中科院科技政策与管理科学研究所,中国高技术产业发展促进会

世界科学技术-中医药现代化

CSTPCD北大核心
影响因子:1.175
ISSN:1674-3849
年,卷(期):2024.26(4)
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