铁皮石斛治疗糖尿病的药理机制研究进展
Research Progress on the Pharmacological Mechanism of Dendrobium Officinale in the Treatment of Diabetes Mellitus
胡学芳 1彭川 1秦灵灵 2吴丽丽 3刘铜华3
作者信息
- 1. 成都中医药大学临床医学院 成都 610075;北京中医药大学中医养生学重点实验室 北京 100029
- 2. 北京中医药大学科技处 北京 100029
- 3. 北京中医药大学中医养生学重点实验室 北京 100029
- 折叠
摘要
石斛是我国名贵中草药之一,铁皮石斛是中药石斛的上品,古代诸多医籍记载其具有治疗糖尿病的功效,作为"药食两用"的中药之一,铁皮石斛被广泛应用.现代药理研究表明,铁皮石斛具有抗肿瘤、抗疲劳、调节免疫、抗衰老以及降糖降脂的作用,在临床运用中,铁皮石斛同样具有平衡糖脂代谢、改善胰岛素抵抗、促进胰岛素分泌、提高胰岛细胞功能的作用,并具有一定的防治糖尿病并发症的作用.目前缺乏铁皮石斛治疗糖尿病的药理机制的系统综述,为更加全面了解现阶段铁皮石斛治疗糖尿病的药理作用,为进一步的药理研究提供参考依据,使其更好的应用于临床,故综述铁皮石斛防治糖尿病的药理作用机制研究进展.
Abstract
Dendrobium is one of the valuable Chinese herbs in China,and Dendrobium officinale is the top grade of Dendrobium,which is recorded in many ancient medical texts as having the efficacy of treating diabetes.Modern pharmacological research shows that Dendrobium has the effects of anti-tumor,anti-fatigue,immune regulation,anti-aging,and regulation of glycolipid metabolism.In clinical application,Dendrobium officinale also has the function of balancing glucose and lipid metabolism,improving insulin resistance,promoting insulin secretion,improving the function of islet cells,and has a certain role in the prevention and treatment of diabetic complications.At present,there is a lack of systematic review of the pharmacological mechanism of Dendrobium officinale in the treatment of diabetes.In order to understand the pharmacological action of Dendrobium officinale in the treatment of diabetes more comprehensively,and to provide a reference for further pharmacological research,so that it can be better applied in clinics,this paper reviews the research progress of the pharmacological mechanism of Dendrobium officinale in the treatment of diabetes.
关键词
铁皮石斛/糖尿病/糖脂代谢/氧化应激/肠道菌群Key words
Dendrobium officinale/Diabetes mellitus/Glycolipid metabolism/Oxidative stress/Intestinal flora引用本文复制引用
基金项目
北京中医药大学横向课题(1130065120002)
出版年
2024
国家科技期刊平台
NSTL
万方数据