病证结合模式下结直肠癌动物模型构建的思考
Considerations on the Construction of Animal Models of Colorectal Cancer Under the Pathology-Evidence Combination Model
郭欣煜 1王菲叶 2许云 2龚璐天 2付力 2曾钰梅 2杨宇飞2
作者信息
- 1. 中国中医科学院西苑医院 北京 100091;北京中医药大学西苑临床医学院 北京 100029
- 2. 中国中医科学院西苑医院 北京 100091
- 折叠
摘要
实验动物模型是结直肠癌基础研究中必不可少的环节.构建以中医辨证论治理论为基础的中医特色的病证结合动物模型,使动物模型既符合西医疾病特征又具备中医证候的特点,对中医药治疗结直肠肿瘤的基础研究有重要意义.本文通过文献梳理的方式总结了当前常用的结直肠肿瘤动物模型和病证结合动物模型的构建方法与特点,以期为从事结直肠肿瘤科学研究的科研工作者提供参考.
Abstract
Experimental animal models are an essential part of basic research on colorectal cancer.It is important for basic research on colorectal tumor treatment in TCM to construct animal models with the characteristics of TCM based on the theory of TCM diagnosis and treatment,so that the animal models can meet the characteristics of both western medicine and TCM symptoms.In this paper,we summarize the methods and characteristics of animal models of colorectal tumors and the combination of disease and evidence for scientific research on colorectal tumors through literature review,in order to provide reference for researchers engaged in scientific research on colorectal tumors.
关键词
结直肠癌/病证结合/动物模型/中医证候Key words
Colorectal cancer/Pathology-evidence combination/Experimental animal models/TCM syndrome引用本文复制引用
基金项目
国家自然科学基金委员会面上项目(82074414)
中国中医科学院科技创新工程重大攻关项目(CI2021A01807)
出版年
2024