首页|基于数据可视化分析郑洪新教授治疗不寐兼郁证的核心组方与用药特色

基于数据可视化分析郑洪新教授治疗不寐兼郁证的核心组方与用药特色

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目的 基于R语言等多种数据挖掘可视化软件,对郑洪新教授治疗不寐兼郁证的临床病例集进行可视化展示,分析其核心组方与用药特色,以期治疗此类病证的临床推广应用。方法 收集郑洪新教授2020。4。28-2024。1。24于辽宁中医药大学附属医院及辽宁中医药大学附属第四医院出诊期间,明确诊断为不寐兼郁证的有效病例237个,录入患者诊疗信息,建立Excel 2023数据库,通过RStudio(4。3。3)、IBM SPSS Modeler18。0、Cytoscape、Origin。2021、Gephi等多种统计与可视化软件对数据进行分析,并总结核心组方与用药特色。结果 通过对郑洪新教授临床病例集的数据挖掘,得出治疗不寐兼郁证的核心关联规则源自《伤寒论》柴胡加龙骨牡蛎汤的"和解少阳枢机"与《备急千金要方》开心散的"开窍、宁心、安神",加减用药特色可分为益气健脾、理气和胃、补益肝肾、解毒消痈、和胃降逆、制酸止痛、清心除烦,镇心安神、养血敛汗、养心安神10类。结论 郑教授治疗不寐兼郁证的核心组方为柴胡加龙骨牡蛎汤合开心散加减,用药特色以调和脾胃为要,调和气血、调和脏腑为重。
Based on Data Visualization to Analysis Professor Zheng Hongxin's Core Prescription and Medication Characteristics in the Treatment of Depression-Related Insomnia
Objective Based on R language and other data mining visualization software,to visually display the clinical case set of Professor Zheng Hongxin in the treatment of depression-related insomnia,analyze its core prescription and medication characteristics,in order to promote the clinical application of such diseases.Methods During 2020.4.28-2024.1.24,Professor Zheng Hongxin treating patients in the Affiliated Hospital and the 4th Affiliated Hospital of Liaoning TCM University,we collected 237 effective cases of"depression-related insomnia".We input patient diagnosis and treatment information,establishing Excel database,in order to analyz the informaton and summarize the core prescription and Professor Zheng Hongxin's medication characteristics by RStudio(4.3.3),IBM SPSS Modeler18.0,Cytoscape,Origin.2021,Gephi and so on statistical and visualization software.Results Through the data mining of Professor Zheng Hongxin's medical record database,it is concluded that professor Zheng medication core association rules from"Treatise on Exogenous Febrile Disease"Chaihu Longgu Muli Decoction from the perspective of coordinating Shaoyang's activities of qi and"Valuable Prescriptions for Emergency"Kaixinsan from the perspective of inducing resuscitation and relieve uneasiness of mind and body.And the drug changes of"depression-related insomnia"can be divided into 10 methods invigorating spleen qi,regulating qi and stomach,tonifying liver and kidney,detoxification and eliminating carbuncle,making the stomach creep normally,inhibiting the production of gastric acid and pain relief,damping down the fire of heart and eliminate annoyance,calming heart down,nourishing blood and reducing sweat,nourishing the mind to calm the nerves.Conclusion The core prescription of Professor Zheng's treatment of depression-related insomnia is the changes of Chaihu Longgu Muli Decoction and Kaixinsan,and the therapeutic characteristic is to emphasize the coordination of the spleen and stomach,qi and blood and the viscera.

Zheng HongxinData visualization analysisDepression-Related InsomniaChaihu Longgu Muli DecoctionKaixinsanThe Experience of the TCM Masters

赵乙川、杨硕、郑洪新

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辽宁中医药大学 沈阳 110847

辽宁中医药大学附属第四医院 沈阳 110101

郑洪新 数据可视化分析 不寐兼郁证 柴胡加龙骨牡蛎汤 开心散 名老中医经验

2024

世界科学技术-中医药现代化
中科院科技政策与管理科学研究所,中国高技术产业发展促进会

世界科学技术-中医药现代化

CSTPCD北大核心
影响因子:1.175
ISSN:1674-3849
年,卷(期):2024.26(9)