首页|肌少-骨质疏松症与肠道菌群相关性研究

肌少-骨质疏松症与肠道菌群相关性研究

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肌少-骨质疏松症是一种肌少症和骨质疏松症并存的退行性代谢综合征,常发生在老年人身上.其特点是骨密度低、肌肉质量下降和力量损失,这些因素会降低生活质量和活动能力.肌肉骨骼系统是人类整体健康的重要决定因素,随着人口老龄化,肌少-骨质疏松症患者日益增多,其治疗方法越来越受到重视.人体肠道中存在一个复杂的菌群,这些菌群影响着肌肉骨骼发育和体内平衡.因此本综述以肠道菌群对肌肉、骨骼的作用为切入点,分析肠道菌群在肌少-骨质疏松症发病机制及治疗中的作用,阐明肌少-骨质疏松症与肠道菌群的相关性,为更好地治疗肌少-骨质疏松症提供新思路.
Study on the Correlation Between Sarcopenia-Osteoporosis and Intestinal Flora
Sarcopenia-osteoporosis is a degenerative metabolic syndrome in which sarcopenia and osteoporosis coexist,often in the elderly.It is characterized by low bone density,decreased muscle mass and loss of strength,factors that can reduce quality of life and mobility.The musculoskeletal system is an important determinant of overall human health,and as the population ages,the number of patients with sarcopenia-osteoporosis is increasing and its treatment is receiving increasing attention.A complex flora exists in the human gut and these flora influence musculoskeletal development and homeostasis in vivo.Therefore,this review takes the role of intestinal flora on muscle and bone as an entry point to analyze the role of intestinal flora in the pathogenesis and treatment of sarcopenia-osteoporosis,to elucidate the correlation between sarcopenia-osteoporosis and intestinal flora,and to provide new ideas for better treatment of sarcopenia-osteoporosis.

Sarcopenia-osteoporosisIntestinal floraIntervention modalityResearch progress

魏巍、王世轩、战丽彬

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辽宁中医药大学附属第二医院 沈阳 110000

辽宁中医药大学创新工程技术中心 沈阳 110000

肌少-骨质疏松症 肠道菌群 干预方式 研究进展

2024

世界科学技术-中医药现代化
中科院科技政策与管理科学研究所,中国高技术产业发展促进会

世界科学技术-中医药现代化

CSTPCD北大核心
影响因子:1.175
ISSN:1674-3849
年,卷(期):2024.26(9)