Exploring the Role of Amino Acids in Cognitive Dysfunction Based on"Spleen Governs Dispersing Essence and Storing Meaning"
Cognitive impairment belongs to the categories of"foolish disease"and"delusional syndrome"in traditional Chinese medicine,the incidence rate is increasing year by year,and regulating amino acid metabolism may be an important mechanism for the treatment of cognitive dysfunction from the spleen.Amino acids are the essence dispersed by the spleen,which can be used as potential biomarkers.Amino acid neurotransmitters are scattered in the brain,convey the meaning of the spleen,and participate in neuronal communication and cognitive activities.The treatment method is mainly to nourish the spleen and invigorate qi,warm yang and strengthen the spleen,nourish yin and nourish the spleen,and also dissolve phlegm,dispel stasis and detoxify,so as to regulate amino acid metabolism,restore the main function of the spleen,and improve cognitive dysfunction.Under the guidance of the theory of"spleen governs dispersing essence and storing meaning",the regulation of amino acid metabolism provides a new theoretical basis and research strategy for the treatment of cognitive dysfunction diseases in traditional Chinese medicine.
Spleen governs dispersing essence and storing meaningAmino acidsCognitive impairmentTreatment based on the spleen