Discussion on the Theory of TCM Spleen-Viscera-State and Cognitive Function from the Perspective of Vivo Electrophysiology and Optogenetics
In vivo electrophysiology and optogenetics techniques are important modalities in neuroscience research.Based on the core idea of Spleen-Viscera-State theory,this paper focuses on two key technologies:in vivo electrophysiology and optogenetics to explore the neural circuit mechanisms,which related to the spleen governing transportation and transformation and eating behavior,fat-brain axis,the spleen sending the nutrient upward and cerebral glucose metabolism,the spleen ruling thinking function and gut-brain axis,and focuses on the close relationship between the connotation of spleen elephant theory and brain cognitive function from multiple levels and perspectives.The article concludes that innovative neural loop research is one of the important strategies for modernizing the interpretation of the spleen elephant theory of traditional Chinese medicine,and provides a neuroscientific theoretical basis for the treatment of cognitive disorders from the spleen theory in traditional Chinese medicine.
Spleen-Viscera-StateCognitive functionIn vivo electrophysiologyOptogeneticsTheoretical discussion
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