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肿瘤患者新冠后状态群特征分布及银桑颗粒临床疗效观察

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目的 旨在探索肿瘤患者新冠后状态群特征分布,观察银桑颗粒干预后新冠后状态群发生情况。方法 本研究为回顾性临床观察,筛选杨宇飞主任2023年1月-2月门诊全部病例1026例,纳入新冠病毒感染的恶性肿瘤患者444例,其中接受银桑颗粒干预患者265例,主要观察指标为恶性肿瘤患者新冠后状态群特征分布,次要观察指标为银桑颗粒干预后新冠后状态群的发生率。结果 本研究的444例患者中男性198例(44。6%)、女性246例(55。4%);平均年龄59。95±12。45岁;新冠后状态群发生频率最高的5个症状依次为乏力、咳嗽、呼吸困难、失眠、心悸;女性较男性新冠后状态群发生率高,差异有统计学意义(P<0。05);发生新冠后状态群组平均年龄高于未发生组平均年龄(62岁vs58岁),两组年龄差异有统计学意义(P<0。05);乳腺癌患者发生新冠后状态群的风险是结肠癌患者的2。9倍(P<0。05);服用银桑颗粒、女性、胃癌是新冠后状态群的保护因素(P<0。05);服用银桑颗粒组较未服用组新冠后状态群发生率低,两组差异有统计学意义(P<0。05)。结论 银桑颗粒干预能够降低肿瘤患者新冠后状态群的发生率。
The Characteristic Distribution of Post-COVID Conditions in Tumor Patients and the Observation of Clinical Efficacy of Yinsang Granules
Objective This study was aimed to explore the characteristic distribution of Post-COVID Conditions in cancer patients and observe the occurrence of Post-COVID Conditions after the intervention of Yinsang granules.Methods This study was a retrospective clinical observation,and a total of 1026 patients in Yang Yufei's outpatient department from January to February 2023 were screened,including 444 malignant tumor patients infected with COVID-19,among which 265 patients received intervention with Yinsang granules.The main observation indicator was the characteristic distribution of Post-COVID Conditions in malignant tumor patients,and the secondary observation indicator was the incidence of Post-COVID Conditions after intervention with Yinsang granules.Results A total of 444 patients with malignant tumors were included in this study,including 198 males(44.6%)and 246 females(55.4%).Average age 59.95±12.45;The five symptoms with the highest frequency of Post-COVID Conditions were fatigue,cough,dyspnea,insomnia and palpitation.The incidence of Post-COVID Conditions was higher in females than in males,and the difference was statistically significant(P<0.05).The average age of Post-COVID Conditions is higher than that of non-Post-COVID Conditions(62 vs 58),and the age difference between the two groups was statistically significant(P<0.05).The risk of developing Post-COVID Conditions in breast cancer patients was 2.9 times higher than that in colon cancer patients(P<0.05).Yinsang granule,female and gastric cancer were the protective factors for the Post-COVID Conditions(P<0.05).The incidence of Post-COVID Conditions was lower in the group taking Yinsang granule than in the group not taking it,and the difference was statistically significant between the two groups(P<0.05).Conclusion Yinsang Granule intervention can reduce the incidence of Post-COVID Conditions in tumor patients.

Cancer patientsPost-COVID conditionsCharacteristic distributionYinsang granules

石秋杰、闫蕴孜、刘剑、乔辰、杨宇飞

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北京市普仁医院 北京 100062

中国中医科学院西苑医院 北京 100091

肿瘤患者 新冠后状态群 特征分布 银桑颗粒

2024

世界科学技术-中医药现代化
中科院科技政策与管理科学研究所,中国高技术产业发展促进会

世界科学技术-中医药现代化

CSTPCD北大核心
影响因子:1.175
ISSN:1674-3849
年,卷(期):2024.26(11)