工业生产对乙交酯纯度的影响
Influence of Industrial Production on Purity of Glycolide
王法庭 1白文娟1
作者信息
- 1. 国家能源集团榆林化工有限公司,陕西 榆林 719000
- 折叠
摘要
聚乙醇酸(PGA)的主要合成方法是利用高纯度的乙交酯进行开环聚合.由于工艺生产中间产物乙交酯的物料状态特殊,化学性质比较活泼,极易和水反应生成酸类物质,受温度影响容易发生变质反应,导致工业生产中获得高纯度的聚合级乙交酯存在诸多困难.在溶剂重结晶提纯乙交酯的过程中,酸和水是影响乙交酯纯度的主要杂质.文章着重对乙交酯合成、提纯工艺选取、溶剂重结晶提纯精制以及聚合级乙交酯储存过程中影响乙交酯纯度的因素进行分析和讨论,提出生产中减小乙交酯中酸、水含量的改进措施.文章通过对影响因素的分析来明确聚合级乙交酯生产过程中的控制指标,对PGA的生产过程具有指导意义.
Abstract
The main synthesis method of polyglycolic acid(PGA)is to use high-purity glycolide for ring-opening polymerization.Due to the special material state of the intermediate product,glycolide,in the production process,and its relatively reactive chemical nature,it is highly prone to react with water to form acidic substances.It is also susceptible to degradation reactions under the influence of temperature,which makes it challenging to obtain high-purity polymer-grade glycolide in industrial production.During the purification of glycolide through solvent recrystallization,acids and water are the main impurities affecting the purity of glycolide.The article focuses on the analysis and discussion of factors affecting the purity of glycolide in the synthesis,purification process selection,solvent recrystallization purification,and storage of polymer-grade glycolide,and proposes improvements to reduce the content of acid and water in glycolide during production.By analyzing the influencing factors,the article clarifies the control indicators in the production process of polymer-grade glycolide,which has guiding significance for the production process of PGA.
关键词
乙交酯/聚乙醇酸/生物降解材料/重结晶/水/酸Key words
Glycolide/Polyglycolic acid/Biodegradable materials/Recrystallization/Water/Acid引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据