Analysis of the Pathogenic Characteristics and Antimicrobial Resistance Characteristics of 29 Strains of Foodborne Shigella
Objective:To analyze the pathogenic characteristics and antimicrobial resistance characteristics of 29 strains of foodborne Shigella.Method:Twenty-nine strains of foodborne Shigella were grouped by serological methods in GB 4789.5-2012,whole genome sequencing and bioinformatics analysis were performed by high-throughput sequencing technology to determine their group types and serotypes,and antimicrobial susceptibility experiments were carried out by microbroth dilution method.Results:Through serological identification and wgSNP analysis,only 2 of the 29 strains of foodborne Shigella were Shigella flexneri,and the remaining 27 strains were Shigella sonnei,and all 29 strains had different degrees of resistance to ampicillin,ampicillin sulbactam,chloramphenicol,ciprofloxacin,cefotaxime,naphtholidine acid,cotrimoxazole and tetracycline,and the resistance rate to cotrimoxazole and naphridixic acid was the highest(100.00%),and the resistance rate to cefotaxime and ciprofloxacin was low,6.90%,respectively and 3.45%.Conclusion:The dominant strain of foodborne Shigella in Linyi city is Shigella sonnei,and the drug resistance situation is severe,and a more personalized treatment plan should be adopted for Shigella infection cases.
NETL
NSTL
万方数据
