D-alodonose,as a new generation sugar,has physiological functions such as low calorie,low metabolic rate,hypoglycemic,fat accumulation inhibition,obesity prevention,and nerve protection.It is considered an ideal substitute for sucrose due to its unique physiological characteristics,pure taste,high safety,and the ability to improve product quality.In this paper,the application of D-alodonose in the fields of food,medicine,daily chemicals,and biology is reviewed.