Methodological Validation of High Performance Liquid Chromatography for the Determination of Natamycin in Pastries and Fruit Juice
In order to verify whether the Baoji Food and Drug Inspection and Testing Center has the ability to carry out the testing project of the new method GB 5009.286-2022 for natamycin.This article uses a high-performance liquid chromatography to analyze natamycin in pastries and fruit juice.The external standard method is used for quantification to verify the linear relationship,detection limit,precision,and recovery rate of this method.The results showed that natamycin exhibited a good linear relationship within the range from 0.5 μg·mL-1 to 10 μg·mL-1,and the detection limit,precision,and recovery rate of the method can meet the requirements of the standard method.Therefore,our laboratory has the ability to detect natamycin.
natamycinexternal standard methodhigh-performance liquid chromatographymethodology validation