The detection of Illegally Added Drugs in Health Food Products Using High-Performance Liquid Chromatography-Quadrupole/Time-of-Flight High-Resolution Mass Spectrometry
An analytical method for the detection of unlawfully added drugs,sibutramine and phenolphthalein,in health food products was established using high-performance liquid chromatography coupled with quadrupole/time-of-flight high-resolution mass spectrometry.Qualitative analysis of sibutramine and phenolphthalein was conducted based on retention time,while quantitative analysis of these two drugs in health food products was performed using the standard curve method.The results showed that a strong linear correlation was observed between the concentrations of the standard solutions of the two drugs and the corresponding detection response,with correlation coefficients(R2)greater than 0.99.This approach is simple,rapid,and precise,indicating its suitability for the screening of illegally added substances in health food products.
high-performance liquid chromatographyquadrupole/time-of-flight high-resolution mass spectrometryhealth food productsillegally added drugs
万方数据
维普
