Determination of Dicamla and Its Metabolite Residues in Milk with Modified QuEChERS-HPLC-MS/MS
Objective:To establish an improved QuEChERS high performance liquid chromatography-tandem mass spectrometry method for the determination of dicamla and its metabolites in milk.Method:The samples were extracted with mixed solution of acetonitrile and 0.1%acetic acid,purified by anhydrous magnesium sulfate and C18,and determined by MRM mode of high performance liquid chromatography-tandem mass spectrometer.Result:The linear correlation coefficients of dichlorosalicylic acid and trivaloba in 2.0～500.0 μg·L-1,3,6-dichlorosalicylic acid and trivaloba were 0.996 0 and 0.999 0,respectively.The recoveries were 76.1%～98.5%and 82.1%～103.9%,and relative standard deviation were 5.3%～7.3%and 5.4%～8.6%,respectively.The limit of quantification was 10 μg·kg-1.Conclusion:The method is simple and accurate,and suitable for the determination of dicamla pesticide residues of dicamba in milk.
high performance liquid chromatography-tandem mass spectrometrymilkdicamla
万方数据
维普
