Objective To systematically evaluate the food safety of Apios fortunei Maxim.as a new food raw material.Methods In accordance with the 2017 revised version of Administrative measures for safety review of new food materials,a series of studies on the Apios fortunei Maxim.were carried out,including the composition analysis,hygienic tests and toxicology tests.Also,combined with survey on eating condition of people at home and abroad and adverse-effect reports,the edible safety of Apios fortunei Maxim.as a new food raw material was evaluted comprehensively.Results The cooked and dried Apios fortunei Maxim.was rich in protein(14.50 g/100 g).And the content of crude polysaccharides and daphnoretin were 14.90 mg/100 g and 2.62 μg/g,respectively.The detection values of heavy metals,pesticides and microorganisms conformed to the provisions of China national food safety standards.The results of acute oral toxicity tests indicated that cooked and dried Apios fortunei Maxim.was actually nontoxic.The results of 3 genotoxicity tests were all negative.The 90 d oral toxicity tests showed that the no observed adverse effect level(NOAEL)of dried Apios fortunei Maxim.was 6.0 g/(kg·bw)and the results of teratogenicity test showed that there was no teratogenicity on female and fetal rats at the test dose,which was according to the NOAEL of 6.0 g/(kg·bw).The same genus of plants,Apios americana Medikus as a traditional crop in North America and Japan had been consumed for many years,population surveys had not reported adverse effects.According to the folk eating habits,it was estimated that the consumption of Apios fortunei Maxim.was about 60-150 g/(person·d).Conclusion Apios fortunei Maxim.is edible-safety as a new food raw material after cooking.However,as special populations,it is not recommended for infants and toddlers without further demonstration.
关键词
罗汉参/新食品原料/食用安全性/风险评估
Key words
Apios fortunei Maxim./new food raw material/edible safety/risk assessment