Determination of 9,9-bis(methoxymethyl)fluorene migration in food contact materials by gas chromatography-mass spectrometry
Objective To establish a method for the determination of the migration of 9,9-bis(methoxymethyl)fluorene in plastic food contact materials and articles by gas chromatography-mass spectrometry.Methods The water-based food simulants were extracted by n-hexane,and the chemical alternative solvents(95%ethanol and isooctane)were directly injected,and the olive oil simulants were extracted with acetonitrile and then injected,and the samples were analyzed by gas chromatography-tandem mass spectrometry and quantified by external standard method.Results A method for the determination of 9,9-bis(methoxymethyl)fluorene in plastic food contact materials was established.The limit of detection was 0.01 mg/kg or mg/L,the limit of quantification was 0.03 mg/kg or mg/L,the recovery rates were 80.0%-110.0%,and the relative standard deviations were 1.2%-6.0%(n=6).The actual samples of 10 kinds of polypropylene(PP)food contact materials were determined by this method,and the detection rate was 10%,and the detection concentration was 0.12 mg/kg.Conclusion The method is sensitive,has high recovery and accuracy,and the limit of detection can meet the requirements of regulations,and can be used for the practical testing of the migration of 9,9-bis(methoxymethyl)fluorene in polypropylene(PP)food contact materials.
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