Research progress on the application of gold nanoclusters in pathogen detection
Pathogenic bacteria has always been a hot topic of social concern,which is one of the important factors to harm food safety and public health.Rapid and accurate detection of pathogenic bacteria is of great significance to people's health and social stability.In recent years,due to the drawbacks of traditional methods such as cumbersome process,low sensitivity and single detection type,researchers have developed various fluorescence sensors for rapid and accurate detection of pathogenic bacteria through reasonable modification of nanoclusters by various means.This paper focused on the physical and chemical properties of gold nanoclusters,summarized the latest research progress of gold nanoclusters for pathogenic bacteria detection from the perspective of direct and indirect reaction from the different modes of action of gold nanoclusters and target bacteria,and discussed and prospects the shortcomings and possible development directions of gold nanoclusters in the future.The aim is to provide reference for the rapid detection of pathogenic bacteria by gold nanoclusters.