Research progress on detection technology of Cronobacter spp.in infant formula food
Cronobacter spp.is a group of foodborne opportunistic pathogens widely present in the natural environment,characterized by their ability to tolerate desiccation and high osmolarity,enabling them to survive for extended periods in dried milk powder.Infant formula products may become contaminated during production,transportation,storage,and even during the reconstitution process.Infection with Cronobacter spp.can lead to severe illnesses such as bacteremia,meningitis,necrotizing enterocolitis in infants,and may result in serious neurological sequelae or even death.Therefore,establishing efficient and accurate detection methods for Cronobacter spp.is crucial for preventing and controlling these diseases,and holds significant importance in ensuring the quality and safety of infant formula products.Currently,the main detection methods for Cronobacter spp.include traditional culture-based methods,molecular biology methods,and immunological methods,with numerous studies in recent years reporting various degrees of improvement and optimization based on these methods.This article systematically reviewed the principles,advantages,and disadvantages of the various detection methods currently available for Cronobacter spp.,aiming to provide a reference for further research in this field and for the optimization and updating of national standards and industry standards.
infant formula foodCronobacter spp.detection technology