In this paper,anthocyanins were extracted from wine grape('Syrah')skins using citric acid solution as extractant.The microwave-assisted extraction method was optimized by signal factor experiment and orthogonal experiment.The results showed that the optimum extracting parameters were as follows:citric acid concentration 2.5%,solid-liquid ratio 1∶30(g/mL),microwave power 750 W,and microwave time 40 min.Under these conditions,the total anthocyanins content was 4.461 mg/g.The results of antioxidant activity showed that the scavenging rates of DPPH and ABTS+free radicals were respectively 76.20%and 96.82%when the concentration of anthocyanins in wine grape pomace reached 2.0 mg/mL,which suggested that it had good antioxidant activity.