Synergistic Effect of the Compound of Plant-Extraction on Gastric Mucosal Protection
Through acute animal experiments,chronic animal experiments,and human trial feeding,explore the effect of plant-extractioncompound(hericiumerinaceus,broccoli,curcuminand aucklandiaeradixincense)on gastric mucosal protection.The experimental setup included a blank control group,a model control group,and three experimental groups of a single component of broccoli,hericiumerinaceus,curcumin and aucklandiae radix incense compound 1,and hericiumerinaceus,broccoli,curcumin and aucklandiae radix compound 2.In acute animal experiments,all three experimental groups showed significant effects,with compound 2 had the best damage inhibition effect.In chronic animal experiments,a single broccoli had no significant effect.Both compound 1 and compound 2 had effects,reducing the area and volume of ulcers,and compound 2 was better than compound 1.The human trial results showed that the combination of hericiumerinaceus,broccoli,curcumin,and aucklandiae radix had a more significant effect on pepsinogen and gastrin,indicating an improvement in the gastric mucosa.There were no significant adverse reactions during the human trial,and the combination of hericiumerinaceus,broccoli,curcumin,and aucklandiae radixhad mild effects.It provides a research foundation for the combined use of hericiumerinaceus,broccoli,curcumin and aucklandiae radix,as well as the development of related foods.