混料试验设计优化黄果梨清咽口服液的配方
Optimization of the Formulation of Huangguo Pear Oral Liquid with Function of Throat-Clearing by Mixture Experiment Design
晁琴 1王树林 1郝颖杰 1本措吉 1杨成娟1
作者信息
- 1. 青海大学农牧学院(西宁 810016)
- 折叠
摘要
筛选一种具有清咽功效的黄果梨口服液配方.采用混料设计研究黄果梨汁、沙棘汁、甘草和贝母提取液不同配比对黄果梨清咽口服液DPPH自由基清除率、OH自由基清除率和总还原力等与清咽功效直接相关的抗氧化能力指标的影响,建立原料配比与黄果梨清咽口服液抗氧化能力和总还原力指标的回归模型,考察配方中各组分的互作效果,并用模糊数学综合评价该产品.结果表明,具有较高抗氧化能力的产品配方为黄果梨汁75％,沙棘汁5％,甘草提取液15％,贝母提取液5％.该配方产品DPPH自由基清除率、OH自由基清除率和总还原力的理论值分别为88.74％,69.33％和0.67,对优化的结果进行3次平行试验,得出的平均值分别为83.80％,69.98％和0.70,按此条件下制作的产品消费者能接受.优化配方后生产的黄果梨口服液具有较高抗氧化能力和较好的感官品质,该研究为黄果梨清咽口服液生产及产品功效评价提供基础.
Abstract
Using Huangguo pear as raw material,one formulation of oral liquid with function of throat-clearing has been optimized by mixture experiment design.Using antioxidant capacity of the product as an indicator of ability of throat-clearing,a mixed design is used to study the effects of different ratios of Huangguo pear and sea buckthom juice,licorice and fritillaria extracts on the DPPH free radical clearance rate,OH free radical clearance rate,and total reducing power of Huangguo pear oral liquid.A regression model is established for the DPPH free radical clearance rate,OH free radical clearance rate and total reducing power with different ratio of raw material,and the product is comprehensively evaluated by fuzzy mathematics.The product formula with high antioxidant capacity has been selected as 75％Huangguo pear juice,5％sea buckthom juice,15％licorice extract and 5％fritillaria extract.The theoretical values of DPPH free radical clearance rate,OH free radical clearance rate,and total reducing power of this formula product are 88.74％,69.33％and 0.67,respectively.Three parallel experiments are conducted on the optimized formulation,and the final actual values are 83.8％,69.98％,and 0.70,respectively.The products under this condition are accepted to consumers.There is a high antioxidant capacity for Huangguo pear oral liquid with throat-clearing function and a good sensory,which can provide base for production of Huangguo pear oral liquid with throat-clearing and efficacy evaluation.
关键词
黄果梨清咽口服液/混料设计/配比/优化Key words
Huangguo pear oral liquid with throat-clear/mixture design/formulation of products/optimization引用本文复制引用
出版年
2024
NETL
NSTL
万方数据