Optimization of the Formulation of Huangguo Pear Oral Liquid with Function of Throat-Clearing by Mixture Experiment Design
Using Huangguo pear as raw material,one formulation of oral liquid with function of throat-clearing has been optimized by mixture experiment design.Using antioxidant capacity of the product as an indicator of ability of throat-clearing,a mixed design is used to study the effects of different ratios of Huangguo pear and sea buckthom juice,licorice and fritillaria extracts on the DPPH free radical clearance rate,OH free radical clearance rate,and total reducing power of Huangguo pear oral liquid.A regression model is established for the DPPH free radical clearance rate,OH free radical clearance rate and total reducing power with different ratio of raw material,and the product is comprehensively evaluated by fuzzy mathematics.The product formula with high antioxidant capacity has been selected as 75％Huangguo pear juice,5％sea buckthom juice,15％licorice extract and 5％fritillaria extract.The theoretical values of DPPH free radical clearance rate,OH free radical clearance rate,and total reducing power of this formula product are 88.74％,69.33％and 0.67,respectively.Three parallel experiments are conducted on the optimized formulation,and the final actual values are 83.8％,69.98％,and 0.70,respectively.The products under this condition are accepted to consumers.There is a high antioxidant capacity for Huangguo pear oral liquid with throat-clearing function and a good sensory,which can provide base for production of Huangguo pear oral liquid with throat-clearing and efficacy evaluation.
Huangguo pear oral liquid with throat-clearmixture designformulation of productsoptimization
NETL
NSTL
万方数据
