Preparation Technology and Evaluation of Multivitamin and Mineral Chewable Tablets
Multivitamin and mineral chewable tablets were prepared with calcium,iron,zinc,vitamin A,vitamin C,and vitamin D as the main active ingredients,sugar alcohol as the filler,polyvinylpyrrolidone K30 as the adhesive,and magnesium stearate as the lubricant.Select the type of filler to be added based on the moisture absorption and flowability of the powder.Through orthogonal experiments,using sensory score as the index,the optimal formula for fillers,adhesives,and lubricants was determined.Prepare tablets according to the best formula and evaluate the weight variation,hardness,fragility,and vitamin stability of the tablets.The results indicated that the product had uniform color,smooth and complete surface,good sensory evaluation results,and stable quality during the stability test when the formula of isomaltulose,povidone K30,and magnesium stearate was 50%,10%,and 1%.It provides a feasible reference for optimizing the production process of multiple vitamin and mineral chewable tablets.
supplementary material screeningprocess researchorthogonal designproduct evaluation