摘要
肌少症是一种与年龄相关的肌肉质量和功能下降疾病,极大增加了老年人骨折、摔伤和死亡风险.其发病机制主要涉及运动神经元缺失、激素失衡和炎症因子与胰岛素抵抗等因素.补充蛋白质、氨基酸、n-3、n-6多不饱和脂肪酸以及维生素等营养素可以有效防治肌少症.文章着重对肌少症的发病机制和营养干预进行了阐述,以期为老年肌少症研究提供参考.
Abstract
Sarcopenia,an age-associated loss of muscle mass and function,greatly increases the risk of fractures,falls,and death in older adults.The pathogenesis of which is mainly involves motor neuron loss,hormone imbalance,inflammatory factors,and insulin resistance,etc.Supplementing nutrients such as protein,amino acid,n-3,n-6 polyunsaturated fatty acids and vitamin and other nutrients can effectively prevent and treat the sarcopenia.This paper focuses on the pathogenesis and nutritional intervention of sarcopenia to provide a reference for the research of sarcopenia.
基金项目
山东省农业科学院农业科技创新工程(CXGC2023A38)
2022年度山东重点扶持区域引进急需紧缺人才项目()
国家科技期刊平台
NSTL
万方数据