人参与蒲公英根配伍对大鼠"上火"症状的调节作用
Regulating Effect of Ginseng in Combination with Dandelion Root on Shanghuo Symptoms in Rats
王佳男 1王慧敏 1章宝栗 1崔福顺 1朴春香 1李官浩 1李红梅 1崔明勋1
作者信息
- 1. 延边大学农学院,吉林延吉 133002
- 折叠
摘要
为改善食用人参出现的"上火"症状,提高人参的普适性,通过动物实验,分别设置正常组、2、4 g/kg人参组以及 2、4 g/kg人参与蒲公英根配伍组进行灌胃 19 d,测量体温、血压及血清中与"上火"相关联的 5-羟色胺(5-HT)、促甲状腺激素(TSH)、皮质酮(CORT)等指标.结果表明,2、4 g/kg人参与蒲公英根配伍组体温及血压均低于人参组,其中 4 g/kg配伍组效果更显著(P<0.05);与正常组比较,人参组 5-HT含量下降,TSH、17-羟皮质类固醇(17-OHCS)、CORT、肿瘤坏死因子-α(TNF-α)含量升高,差异均有统计学意义(P<0.05);与人参组相比,2、4 g/kg人参与蒲公英根配伍组 5-HT含量升高,TSH、17-OHCS、CORT、TNF-α含量下降,差异均有统计学意义(P<0.05).由此表明,利用人参与蒲公英根配伍可提高人参和蒲公英根价值,调节食用人参引起的"上火"症状.
Abstract
In order to improve the symptoms of"Shanghuo"and the universality of ginseng,the animals randomly divided into control group,the 2 and 4 g/kg ginseng group and ginseng dandelion root compatibility group were given intragastric administration for 19 days,respectively.Body temperature,blood pressure and 5-hydroxytryptamine(5-HT),thyroid-stimulating hormone(TSH),corticosterone(CORT)and other indicators associated with"Shanghuo"were measured.The results showed that the body temperature and blood pressure of the 2 and 4 g/kg groups were lower than those of the ginseng group,and the effect of the 4 g/kg group was more significant(P<0.05).Compared with the control group,the content of 5-HT in ginseng group decreased,and the contents of TSH,17-hydroxy corticosteroid(17-OHCS),CORT,tumor necrosis factor-α(TNF-α)were significantly increased(P<0.05).Compared with ginseng group,the contents of 5-HT in the combination group of 2 and 4 g/kg ginseng and dandelion root compatibility group were increased,and the contents of TSH,17-OHCS,CORT,TNF-α were significantly decreased(P<0.05).The results indicated that compatibility of ginseng and dandelion root could improve the value of ginseng and dandelion root,and regulate the symptoms of"Shanghuo"caused by ginseng consumption.
关键词
人参/蒲公英根/配伍/"上火"/血压Key words
ginseng/dandelion root/compatibility/"Shanghuo"/blood pressure引用本文复制引用
基金项目
吉林省科技专项(20200504002YY)
省科技厅重点研发项目(2020040429YY)
出版年
2024
国家科技期刊平台
NSTL
万方数据