摘要
岩藻黄素(Fucoxanthin)是一种类胡萝卜素,呈红褐色,主要来源于褐藻和硅藻等海洋生物,因其独特的化学结构和丰富的生物活性而引起了广泛的科研兴趣.研究表明,岩藻黄素具有显著的抗炎和抗癌活性,其抗炎作用机制主要包括抑制氧化应激、调控炎症因子、诱导细胞自噬和抵抗细胞凋亡等,抗癌作用机制主要包括诱导细胞自噬与凋亡机制、调控细胞周期、抑制细胞迁移和细胞侵袭等多个方面.本文对岩藻黄素的抗炎、抗癌活性及相关作用机制的研究进展进行简要概述,为进一步深入研究及开发岩藻黄素提供理论基础和借鉴.
Abstract
Fucoxanthin is a carotenoid,reddish-brown in color,which is mainly derived from marine organisms such as brown algae and diatoms,and has aroused extensive scientific interest due to its unique chemical structure and abundant biological activities.Studies have shown that fucoxanthin processes significant anti-inflammatory and anti-cancer activities.Its anti-inflammatory mechanisms primarily include inhibiting oxidative stress,regulating inflammatory factors,inducting cell autophagy,and resisting cell apoptosis,etc.The main mechanism of anti-cancer activity includes inducing cell autophagy and apoptosis mechanisms,regulating the cell cycle,inhibiting cell migration,and suppressing cell invasion,among other aspects.In this paper,the research progress of anti-inflammatory and anti-cancer activities and related mechanisms of action of fucoxanthin is briefly summarized,which provides the theoretical basis and reference for further research and development of fucoxanthin.
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